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Linrong Lu

Shanghai Immune Therapy Institute

Renji Hospital, Shanghai Jiao Tong University School of Medicine

BIOGRAPHY

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PUBLICATIONS

Tespa1 negatively regulates FcεRI-mediated signaling and the mast cell-mediated allergic response.

The Journal of experimental medicine Dec, 2014 | Pubmed ID: 25422497

Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1.

The Journal of experimental medicine May, 2017 | Pubmed ID: 28400474

Phosphatase PP2A is essential for T17 differentiation.

Proceedings of the National Academy of Sciences of the United States of America Jan, 2019 | Pubmed ID: 30593560

Protein phosphatase 2A has an essential role in promoting thymocyte survival during selection.

Proceedings of the National Academy of Sciences of the United States of America Jun, 2019 | Pubmed ID: 31152132

Thymic-specific regulation of TCR signaling by Tespa1.

Cellular & molecular immunology Dec, 2019 | Pubmed ID: 31316154

Dual roles of misshapen/NIK-related kinase (MINK1) in osteoarthritis subtypes through the activation of TGFβ signaling.

Osteoarthritis and cartilage Jan, 2020 | Pubmed ID: 31647983

Thymocyte selection: From signaling to epigenetic regulation.

Advances in immunology , 2019 | Pubmed ID: 31699214

Therapeutic efficacy of anti-CD19 CAR-T cells in a mouse model of systemic lupus erythematosus.

Cellular & molecular immunology Aug, 2021 | Pubmed ID: 32472023

Mobilizing ER IP3 receptors as a mechanism to enhance calcium signaling.

Cellular & molecular immunology Sep, 2021 | Pubmed ID: 34253857

Priming of NLRP3 inflammasome activation by Msn kinase MINK1 in macrophages.

Cellular & molecular immunology Oct, 2021 | Pubmed ID: 34480147

CAR-T cell therapy: new hope for systemic lupus erythematosus patients.

Cellular & molecular immunology Dec, 2021 | Pubmed ID: 34737415

NPAT Supports CD8 Immature Single-Positive Thymocyte Proliferation and Thymic Development.

Journal of immunology (Baltimore, Md. : 1950) Sep, 2022 | Pubmed ID: 35922064

Protein phosphatase 2A propels follicular T helper cell development in lupus.

Journal of autoimmunity Apr, 2023 | Pubmed ID: 37001432

GRP75-dependent mitochondria-ER contacts ensure cell survival during early mouse thymocyte development.

Developmental cell Oct, 2024 | Pubmed ID: 38981469

INSTITUTIONS

Renji Hospital, Shanghai Jiao Tong University School of Medicine

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

JOVE ARTICLES

Retroviral CRISPR/Cas9-Mediated Gene Targeting for the Study of Th17 Differentiation in Vitro

Zejin Cui^*,1,

Pengkun Yuan^*,2,

Zhishan Zhao^*,1,

Fan Zhao³,

Linrong Lu^1,3

¹Shanghai Immune Therapy Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine,

²Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine, Zhejiang University,

³Institute of Immunology and Department of Rheumatology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

Immunology and Infection

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Linrong Lu

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Renji Hospital, Shanghai Jiao Tong University School of Medicine

Retroviral CRISPR/Cas9-Mediated Gene Targeting for the Study of Th17 Differentiation in Vitro

Shanghai Immune Therapy Institute