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Leslie Dan Faculty of Pharmacy
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Bioorthogonal phase-directed copper-catalyzed azide-alkyne cycloaddition (PDCuAAC) coupling of selectively cross-linked superoxide dismutase dimers produces a fully active bis-dimer.
Organic & biomolecular chemistry Oct, 2015 | Pubmed ID: 26308144
Subunit-directed click coupling via doubly cross-linked hemoglobin efficiently produces readily purified functional bis-tetrameric oxygen carriers.
Organic & biomolecular chemistry Dec, 2015 | Pubmed ID: 26400017
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin-Avidin Interactions.
Biochemistry May, 2016 | Pubmed ID: 27126305
Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier.
Organic & biomolecular chemistry Oct, 2016 | Pubmed ID: 27714247
Cross-linked hemoglobin bis-tetramers from bioorthogonal coupling do not induce vasoconstriction in the circulation.
Transfusion 01, 2019 | Pubmed ID: 30444016
Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
Journal of molecular biology Sep, 2021 | Pubmed ID: 34329642
A Quantitative Assay for Ca Uptake through Normal and Pathological Hemichannels.
International journal of molecular sciences Jun, 2022 | Pubmed ID: 35806342
University of Toronto
Masoud Norouzi1,
Riham Zayeni1,
Serena Singh1,
Keith Pardee1,2
1Leslie Dan Faculty of Pharmacy, University of Toronto,
2Department of Mechanical and Industrial Engineering, University of Toronto
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