Department of Neurosurgery
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Trophic activity of Rabies G protein-pseudotyped equine infectious anemia viral vector mediated IGF-I motor neuron gene transfer in vitro.
Neurobiology of disease Dec, 2005 | Pubmed ID: 16005636
A novel peptide defined through phage display for therapeutic protein and vector neuronal targeting.
Neurobiology of disease Aug, 2005 | Pubmed ID: 16023583
Gene-based treatment of motor neuron diseases.
Muscle & nerve Mar, 2006 | Pubmed ID: 16228969
X-Linked inhibitor of apoptosis protein gene-based neuroprotection for the peripheral nervous system.
Neurosurgery Jul, 2006 | Pubmed ID: 16823314
Neuronal affinity of a C7C loop peptide identified through phage display.
Journal of drug targeting Jun, 2006 | Pubmed ID: 16882546
Viral clostridial light chain gene-based control of penicillin-induced neocortical seizures.
Molecular therapy : the journal of the American Society of Gene Therapy Mar, 2007 | Pubmed ID: 17213837
Ribonucleic acid interference for neurological disorders: candidate diseases, potential targets, and current approaches.
Neurosurgery Jan, 2007 | Pubmed ID: 17228249
A means for targeting therapeutics to peripheral nervous system neurons with axonal damage.
Neurosurgery May, 2007 | Pubmed ID: 17460527
Reversible unilateral nigrostriatal pathway inhibition induced through expression of adenovirus-mediated clostridial light chain gene in the substantia nigra.
Neuromolecular medicine , 2007 | Pubmed ID: 17914186
Gene therapy for peripheral nervous system diseases.
Current gene therapy Aug, 2007 | Pubmed ID: 17969557
Targeted spinal cord therapeutics delivery: stabilized platform and microelectrode recording guidance validation.
Stereotactic and functional neurosurgery , 2008 | Pubmed ID: 18073518
Ribonucleic acid interference: the relevance of molecular targeting and therapeutics to neurosurgical practice.
Clinical neurosurgery , 2007 | Pubmed ID: 18504906
Fusion of the tetanus toxin C fragment binding domain and Bcl-xL for protection of peripheral nerve neurons.
Neurosurgery Dec, 2008 | Pubmed ID: 19057331
Intraspinal cord delivery of IGF-I mediated by adeno-associated virus 2 is neuroprotective in a rat model of familial ALS.
Neurobiology of disease Mar, 2009 | Pubmed ID: 19135533
Comparative analysis of HIV-1-based lentiviral vectors bearing lyssavirus glycoproteins for neuronal gene transfer.
Genetic vaccines and therapy , 2009 | Pubmed ID: 19144125
Optogenetic neuromodulation.
Neurosurgery May, 2009 | Pubmed ID: 19404144
A conditioning lesion provides selective protection in a rat model of Amyotrophic Lateral Sclerosis.
PloS one , 2009 | Pubmed ID: 19806196
Cervical spinal cord therapeutics delivery: preclinical safety validation of a stabilized microinjection platform.
Neurosurgery Oct, 2009 | Pubmed ID: 19834381
Invited review: festschrift edition of neurosurgery peripheral nervous system as a conduit for delivering therapies for diabetic neuropathy, amyotrophic lateral sclerosis, and nerve regeneration.
Neurosurgery Oct, 2009 | Pubmed ID: 19927084
Viral vector-mediated gene transfer for CNS disease.
Expert opinion on biological therapy Mar, 2010 | Pubmed ID: 20132059
Preclinical safety validation of a stabilized viral vector direct injection approach to the cervical spinal cord.
Clinical and translational science Apr, 2009 | Pubmed ID: 20443884
Cervical multilevel intraspinal stem cell therapy: assessment of surgical risks in Gottingen minipigs.
Spine Feb, 2011 | Pubmed ID: 21099736
Stem cell technology for the study and treatment of motor neuron diseases.
Regenerative medicine Mar, 2011 | Pubmed ID: 21391854
Comparison of adeno-associated viral vector serotypes for spinal cord and motor neuron gene delivery.
Human gene therapy Sep, 2011 | Pubmed ID: 21443428
Platform and cannula design improvements for spinal cord therapeutics delivery.
Neurosurgery Dec, 2011 | Pubmed ID: 21471842
Surgical approach and safety of spinal cord stem cell transplantation.
Neurosurgery Feb, 2011 | Pubmed ID: 21654562
Pain in amyotrophic lateral sclerosis: a neglected aspect of disease.
Neurology research international , 2011 | Pubmed ID: 21766021
Assessment of hippocampal adeno-associated viral vector gene delivery via frameless stereotaxis in a nonhuman primate.
Stereotactic and functional neurosurgery , 2011 | Pubmed ID: 21849811
Intramuscular administration of a VEGF zinc finger transcription factor activator (VEGF-ZFP-TF) improves functional outcomes in SOD1 rats.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases Sep, 2011 | Pubmed ID: 21864053
Gene therapy for amyotrophic lateral sclerosis.
Neurobiology of disease Nov, 2012 | Pubmed ID: 21889591
Translational stem cell therapy for amyotrophic lateral sclerosis.
Nature reviews. Neurology Dec, 2011 | Pubmed ID: 22158518
Characterization of a murine model of SMA.
Neurobiology of disease Mar, 2012 | Pubmed ID: 22198571
Lumbar intraspinal injection of neural stem cells in patients with amyotrophic lateral sclerosis: results of a phase I trial in 12 patients.
Stem cells (Dayton, Ohio) Jun, 2012 | Pubmed ID: 22415942
Intraspinal stem cell transplantation in amyotrophic lateral sclerosis: a phase I safety trial, technical note, and lumbar safety outcomes.
Neurosurgery Aug, 2012 | Pubmed ID: 22565043
Thais Federici1,
Carl V. Hurtig1,
Kentrell L. Burks1,
Jonathan P. Riley1,
Vibhor Krishna2,
Brandon A. Miller1,
Eric A. Sribnick1,
Joseph H. Miller3,
Natalia Grin1,
Jason J. Lamanna1,4,5,
Nicholas M. Boulis1
1Department of Neurosurgery, Emory University,
2Department of Neuroscience, Medical University of South Carolina,
3Division of Neurosurgery, University of Alabama, Birmingham,
4Department of Biomedical Engineering, Georgia Institute of Technology ,
5Department of Biomedical Engineering, Emory University
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