Brian Seed

Identification of a novel Ras-regulated proapoptotic pathway.

Site-specific gene targeting in mouse embryonic stem cells with intact bacterial artificial chromosomes.

Selection of oligonucleotide probes for protein coding sequences.

Dynamic imaging of collagen and its modulation in tumors in vivo using second-harmonic generation.

The cell adhesion protein P-selectin glycoprotein ligand-1 is a substrate for the aspartyl protease BACE1.

A PCR primer bank for quantitative gene expression analysis.

Epstein-Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK alpha-dependent noncanonical NF-kappaB activation.

The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death.

Discs large (Dlg1) complexes in lymphocyte activation.

The knockout mouse project.

Differential transplantability of tumor-associated stromal cells.

Identification of eosinophil lineage-committed progenitors in the murine bone marrow.

PDZ domains and the politics of polarity in lymphocytes.

Large-scale screens for cDNAs with in vivo activity.

B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells.

Expression cloning screen for modifiers of amyloid precursor protein shedding.

CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma.

A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies.

Direct stimulation of T lymphocytes by immunosomes: virus-like particles decorated with T cell receptor/CD3 ligands plus costimulatory molecules.

ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol.

General strategy for decoration of enveloped viruses with functionally active lipid-modified cytokines.

Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes.

A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.

A pathway sensor for genome-wide screens of intracellular proteolytic cleavage.

Spinophilin and the immune synapse.

Quantitation of autophagy by luciferase release assay.

A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance.

Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.

Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules.

O-Spiro C-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.

Exploration of O-spiroketal C-arylglucosides as novel and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.

PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantification.

Fluorosomes: a convenient new reagent to detect and block multivalent and complex receptor-ligand interactions.

Host-encoded reporters for the detection and purification of multiple enveloped viruses.

Conformationally constrained spiro C-arylglucosides as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.

Activating WASP mutations associated with X-linked neutropenia result in enhanced actin polymerization, altered cytoskeletal responses, and genomic instability in lymphocytes.

Mice lacking Dok-1, Dok-2, and Dok-3 succumb to aggressive histiocytic sarcoma.

ortho-Substituted C-aryl glucosides as highly potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors.

The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3.

EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA(1c) levels in db/db mice and prolongs the survival of stroke-prone rats.

C-aryl glucosides substituted at the 4'-position as potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Phosphoprotein associated with glycosphingolipid-enriched microdomains differentially modulates SRC kinase activity in brain maturation.

PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update.

STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells.

Enhanced tim3 activity improves survival after influenza infection.