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Department of Pathology
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Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development.
Science (New York, N.Y.) Apr, 2002 | Pubmed ID: 11935030
Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene.
Nature immunology Jan, 2005 | Pubmed ID: 15580273
Transcriptional regulation in early B cell development.
Current opinion in immunology Apr, 2007 | Pubmed ID: 17292598
Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes.
Nature immunology Apr, 2007 | Pubmed ID: 17334367
Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2007 | Pubmed ID: 17911612
Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.
Immunity Mar, 2008 | Pubmed ID: 18280186
Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells.
Nature immunology Apr, 2008 | Pubmed ID: 18297074
Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.
PloS one , 2008 | Pubmed ID: 18974788
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.
Nature immunology Jun, 2009 | Pubmed ID: 19448632
Chromosome dynamics and the regulation of V(D)J recombination.
Immunological reviews Sep, 2010 | Pubmed ID: 20727028
Epigenetic regulation of V(D)J recombination.
Essays in biochemistry Sep, 2010 | Pubmed ID: 20822496
It takes two: communication between homologous alleles preserves genomic stability during V(D)J recombination.
Nucleus (Austin, Tex.) Jan-Feb, 2010 | Pubmed ID: 21327101
The RAG2 C terminus suppresses genomic instability and lymphomagenesis.
Nature Mar, 2011 | Pubmed ID: 21368836
RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation.
Immunity Mar, 2011 | Pubmed ID: 21435585
A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location.
Journal of immunology (Baltimore, Md. : 1950) May, 2011 | Pubmed ID: 21441452
V(D)J recombination: a paradigm for studying chromosome interactions in mammalian cells.
Epigenomics Apr, 2010 | Pubmed ID: 22121867
Equal opportunity for all.
The EMBO journal Apr, 2012 | Pubmed ID: 22415367
The role of CTCF in regulating V(D)J recombination.
Current opinion in immunology Apr, 2012 | Pubmed ID: 22424610
IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2012 | Pubmed ID: 22581861
Close proximity to Igh is a contributing factor to AID-mediated translocations.
Molecular cell Sep, 2012 | Pubmed ID: 22864115
New York University School of Medicine
Julie Chaumeil1,
Mariann Micsinai1,2,3,4,
Jane A. Skok1
1Department of Pathology, New York University School of Medicine,
2, New York University Center for Health Informatics and Bioinformatics,
3, NYU Cancer Institute,
4Department of Pathology and Yale Cancer Center, Yale University School of Medicine
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