Fred E. Regnier

Comparative proteomics based on stable isotope labeling and affinity selection.

Quantifying peptides in isotopically labeled protease digests by ion mobility/time-of-flight mass spectrometry.

Quantitative proteomics strategy involving the selection of peptides containing both cysteine and histidine from tryptic digests of cell lysates.

Global internal standard technology for comparative proteomics.

Controlling deuterium isotope effects in comparative proteomics.

Protein proteolysis and the multi-dimensional electrochromatographic separation of histidine-containing peptide fragments on a chip.

Minimizing resolution of isotopically coded peptides in comparative proteomics.

An isotope coding strategy for proteomics involving both amine and carboxyl group labeling.

Stopped-flow enzyme assays on a chip using a microfabricated mixer.

Regio-specific adsorption of cytochrome c on negatively charged surfaces.

Capillary electrochromatography of peptides on microfabricated poly(dimethylsiloxane) chips modified by cerium(IV)-catalyzed polymerization.

Histidine-rich peptide selection and quantification in targeted proteomics.

Effect of microenvironment pH of aluminum hydroxide adjuvant on the chemical stability of adsorbed antigen.

Potential of silica monolithic columns in peptide separations.

Contributions of commercial sorbents to the selectivity in immobilized metal affinity chromatography with Cu(II).

Proteomic analysis of Arabidopsis glutathione S-transferases from benoxacor- and copper-treated seedlings.

High-speed label-free detection by spinning-disk micro-interferometry.

Proteomic analysis of carbonylated proteins in two-dimensional gel electrophoresis using avidin-fluorescein affinity staining.

Enrichment of cysteine-containing peptides from tryptic digests using a quaternary amine tag.

New approach for analysis of the phosphotyrosine proteome and its application to the chicken B cell line, DT40.

Benzoyl derivatization as a method to improve retention of hydrophilic peptides in tryptic peptide mapping.

Optimization of diagonal chromatography for recognizing post-translational modifications.

Processing of data generated by 2-dimensional gel electrophoresis for statistical analysis: missing data, normalization, and statistics.

Use of multidimensional lectin affinity chromatography in differential glycoproteomics.

An automated method for the analysis of stable isotope labeling data in proteomics.

Recent advancements in differential proteomics based on stable isotope coding.

Comparative glycoproteomics of N-linked complex-type glycoforms containing sialic acid in human serum.

Primary amine coding as a path to comparative proteomics.

Enhancement of amino acid detection and quantification by electrospray ionization mass spectrometry.

Targeted glycoproteomics: serial lectin affinity chromatography in the selection of O-glycosylation sites on proteins from the human blood proteome.

Neural network prediction of peptide separation in strong anion exchange chromatography.

Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease.

An isotope coding strategy for proteomics involving both amine and carboxyl group labeling.

Enhancement of the LC/MS analysis of fatty acids through derivatization and stable isotope coding.

Adaptive interferometry of protein on a BioCD.

Differential metabolomics using stable isotope labeling and two-dimensional gas chromatography with time-of-flight mass spectrometry.

Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry peak sorting algorithm.

Two-dimensional correlation optimized warping algorithm for aligning GC x GC-MS data.

Use of glycan targeting antibodies to identify cancer-associated glycoproteins in plasma of breast cancer patients.

Simultaneous quantification of metabolites involved in central carbon and energy metabolism using reversed-phase liquid chromatography-mass spectrometry and in vitro 13C labeling.

Comparative metabolite profiling of carboxylic acids in rat urine by CE-ESI MS/MS through positively pre-charged and (2)H-coded derivatization.

Glycoproteomics of plasma based on narrow selectivity lectin affinity chromatography.

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma.

Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses.

Interlaboratory study characterizing a yeast performance standard for benchmarking LC-MS platform performance.

Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry.

Oxidative stress studies in yeast with a frataxin mutant: a proteomics perspective.

Sweetening the pot: adding glycosylation to the biomarker discovery equation.

In vitro stable isotope labeling for discovery of novel metabolites by liquid chromatography-mass spectrometry: Confirmation of gamma-tocopherol metabolism in human A549 cell.

Protein-based multiplex assays: mock presubmissions to the US Food and Drug Administration.

Analytical validation of protein-based multiplex assays: a workshop report by the NCI-FDA interagency oncology task force on molecular diagnostics.

Profiling carbonylated proteins in human plasma.

Multi-dimensional liquid chromatography in proteomics--a review.

Screening antibody and immunosorbent selectivity by two-dimensional liquid chromatography-MS/MS (2-D LC-MS/MS).

Proteomic identification of carbonylated proteins and their oxidation sites.

A lectin affinity workflow targeting glycosite-specific, cancer-related carbohydrate structures in trypsin-digested human plasma.

Sialylated Lewis x antigen bearing glycoproteins in human plasma.

Dynamics of protein damage in yeast frataxin mutant exposed to oxidative stress.

Coupling protein complex analysis to peptide based proteomics.

A large, consistent plasma proteomics data set from prospectively collected breast cancer patient and healthy volunteer samples.

Differential carbonylation of proteins as a function of in vivo oxidative stress.

Oxidative stress induced carbonylation in human plasma.

Determining the effects of antioxidants on oxidative stress induced carbonylation of proteins.

Effect of Single Amino Acid Substitution on Oxidative Modifications of the Parkinson's Disease-Related Protein, DJ-1.

A lectin chromatography/mass spectrometry discovery workflow identifies putative biomarkers of aggressive breast cancers.