Philippe Georgel

Chromatin structure of eukaryotic promoters: a changing perspective.

Differential core histone binding behavior: RNA polymerase I promoter region vs 5S rDNA positioning DNA sequences.

The Drosophila immune defense against gram-negative infection requires the death protein dFADD.

Quantitative characterization of specific genomic promoters using agarose gel electrophoresis.

Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation.

Formation of higher-order secondary and tertiary chromatin structures by genomic mouse mammary tumor virus promoters.

Lps2 and signal transduction in sepsis: at the intersection of host responses to bacteria and viruses.

Biophysical analysis of specific genomic loci assembled as chromatin in vivo.

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection.

To the 30-nm chromatin fiber and beyond.

Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules.

Genetic analysis of innate immunity: TIR adapter proteins in innate and adaptive immune responses.

Genetic dissection of innate immunity to infection: the mouse cytomegalovirus model.

CD36 is a sensor of diacylglycerides.

CD14 is required for MyD88-independent LPS signaling.

Genetic analysis of innate immunity: identification and function of the TIR adapter proteins.

A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria.

Chromatin remodeling complexes: ATP-dependent machines in action.

Chromatin potentiation of the hsp70 promoter is linked to GAGA-factor recruitment.

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.

Genetic analysis of innate resistance to mouse cytomegalovirus (MCMV).

R-form LPS, the master key to the activation ofTLR4/MD-2-positive cells.

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large.

Characterization of chromatin samples in the presence of Drosophila embryo extract by quantitative agarose gel electrophoresis.

Analysis of the MCMV resistome by ENU mutagenesis.

HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription.

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis.

GAGA protein: a multi-faceted transcription factor.

Genetic analysis of innate immunity.

Cell-associated double-stranded RNA enhances antitumor activity through the production of type I IFN.

[Toll-dependent and toll-independent innate antiviral immunity].

Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway.

The use of Quantitative Agarose Gel Electrophoresis for rapid analysis of the integrity of protein-DNA complexes.

Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression.

CHD proteins: a diverse family with strong ties.

Role of chromatin/epigenetic modifications on DNA accessibility.

TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages.

ENU mutagenesis in mice.

Role of nucleic acid binding in Sir3p-dependent interactions with chromatin fibers.

Chromatin stability at low concentration depends on histone octamer saturation levels.

Genetic and epigenetic regulations of prostate cancer by genistein.

The heterogeneous allelic repertoire of human toll-like receptor (TLR) genes.

Silencing and re-expression of retinoic acid receptor beta2 in human melanoma.

Virus-host interactions in hepatitis C virus infection: implications for molecular pathogenesis and antiviral strategies.

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells.

The non-conventional MHC class I MR1 molecule controls infection by Klebsiella pneumoniae in mice.

MeCP2: structure and function.

Identification of Mouse Cytomegalovirus Resistance Loci by ENU Mutagenesis.

TLR2 expression is regulated by microRNA miR-19 in rheumatoid fibroblast-like synoviocytes.

MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain.

Deregulation of type I IFN-dependent genes correlates with increased susceptibility to cytomegalovirus acute infection of dicer mutant mice.

MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes.

ENU-induced phenovariance in mice: inferences from 587 mutations.

The miR-17 ∼ 92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis.