Mark M. Metzstein

Branching morphogenesis of the Drosophila tracheal system.

Functions of the nonsense-mediated mRNA decay pathway in Drosophila development.

The zinc-finger protein Zelda is a key activator of the early zygotic genome in Drosophila.

The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy.

Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice.

A novel function for the PAR complex in subcellular morphogenesis of tracheal terminal cells in Drosophila melanogaster.

Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6.

Drosophila Zpr1 (Zinc finger protein 1) is required downstream of both EGFR and FGFR signaling in tracheal subcellular lumen formation.