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INSERM U1052,
CNRS UMR5286
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Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function.
Oncogene Mar, 2002 | Pubmed ID: 11948405
Recurrent involvement of the MLL gene in adult T-lineage acute lymphoblastic leukemia.
Blood Jun, 2002 | Pubmed ID: 12066788
Regulation of human erythropoiesis by activin A, BMP2, and BMP4, members of the TGFbeta family.
Experimental cell research Jan, 2003 | Pubmed ID: 12531697
Drosophila TGIF proteins are transcriptional activators.
Molecular and cellular biology Dec, 2003 | Pubmed ID: 14645536
FLRG, a new ADAM12-associated protein, modulates osteoclast differentiation.
Biology of the cell / under the auspices of the European Cell Biology Organization Jul, 2005 | Pubmed ID: 15574124
A novel role for fibronectin type I domain in the regulation of human hematopoietic cell adhesiveness through binding to follistatin domains of FLRG and follistatin.
Experimental cell research Feb, 2006 | Pubmed ID: 16336961
TGIF inhibits retinoid signaling.
Molecular and cellular biology Feb, 2006 | Pubmed ID: 16428452
The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells.
Cancer letters Feb, 2007 | Pubmed ID: 16616811
Functional analysis of mutations in TGIF associated with holoprosencephaly.
Molecular genetics and metabolism Jan, 2007 | Pubmed ID: 16962354
Identification of NF-kappaB responsive elements in follistatin related gene (FLRG) promoter.
Gene May, 2007 | Pubmed ID: 17395406
Silencing of FLRG, an antagonist of activin, inhibits human breast tumor cell growth.
Cancer research Aug, 2007 | Pubmed ID: 17671190
AF10-dependent transcription is enhanced by its interaction with FLRG.
Biology of the cell / under the auspices of the European Cell Biology Organization Oct, 2007 | Pubmed ID: 17868029
Maternal Tgif is required for vascularization of the embryonic placenta.
Developmental biology Jul, 2008 | Pubmed ID: 18508043
Generation of mice with conditionally activated transforming growth factor beta signaling through the TbetaRI/ALK5 receptor.
Genesis (New York, N.Y. : 2000) Dec, 2008 | Pubmed ID: 18821589
iNKT cell development is orchestrated by different branches of TGF-beta signaling.
The Journal of experimental medicine Jun, 2009 | Pubmed ID: 19451264
Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.
PLoS genetics Jul, 2009 | Pubmed ID: 19629168
A rapid strategy to detect the recombined allele in LSL-TβRICA transgenic mice.
Genesis (New York, N.Y. : 2000) Sep, 2010 | Pubmed ID: 20645310
Tif1γ suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway.
The American journal of pathology Jun, 2012 | Pubmed ID: 22469842
Premature senescence and increased TGFβ signaling in the absence of Tgif1.
PloS one , 2012 | Pubmed ID: 22514746
The human NUPR1/P8 gene is transcriptionally activated by transforming growth factor β via the SMAD signalling pathway.
The Biochemical journal Jul, 2012 | Pubmed ID: 22738338
Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer.
EMBO molecular medicine Sep, 2012 | Pubmed ID: 22821859
Generation of a conditional mouse model to target Acvr1b disruption in adult tissues.
Genesis (New York, N.Y. : 2000) Feb, 2013 | Pubmed ID: 23109354
The conditional expression of KRAS G12D in mouse pancreas induces disorganization of endocrine islets prior the onset of ductal pre-cancerous lesions.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] May-Jun, 2013 | Pubmed ID: 23719586
Centre de Recherche en Cancérologie de Lyon
Université de Lyon
Université Lyon 1
Centre Léon Bérard
Johann Gout1,2,3,4,5,
Roxane M. Pommier1,2,3,4,5,
David F. Vincent1,2,3,4,5,
Bastien Kaniewski1,2,3,4,5,
Sylvie Martel1,2,3,4,5,
Ulrich Valcourt*,1,2,3,4,5,
Laurent Bartholin*,1,2,3,4,5
1INSERM U1052, Centre de Recherche en Cancérologie de Lyon,
2CNRS UMR5286, Centre de Recherche en Cancérologie de Lyon,
3, Université de Lyon,
4, Université Lyon 1,
5, Centre Léon Bérard
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