Bevin P. Engelward

Nitric oxide-induced homologous recombination in Escherichia coli is promoted by DNA glycosylases.

Base excision repair and nucleotide excision repair contribute to the removal of N-methylpurines from active genes.

Spontaneous mitotic homologous recombination at an enhanced yellow fluorescent protein (EYFP) cDNA direct repeat in transgenic mice.

Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses.

New immunoaffinity-LC-MS/MS methodology reveals that Aag null mice are deficient in their ability to clear 1,N6-etheno-deoxyadenosine DNA lesions from lung and liver in vivo.

"Recombomice": the past, present, and future of recombination-detection in mice.

In vivo recombination after chronic damage exposure falls to below spontaneous levels in "recombomice".

Delineation of the chemical pathways underlying nitric oxide-induced homologous recombination in mammalian cells.

Interstrand crosslink-induced homologous recombination carries an increased risk of deletions and insertions.

A single acute exposure to a chemotherapeutic agent induces hyper-recombination in distantly descendant cells and in their neighbors.

Threshold effects of nitric oxide-induced toxicity and cellular responses in wild-type and p53-null human lymphoblastoid cells.

Homologous recombination prevents methylation-induced toxicity in Escherichia coli.

Age-dependent accumulation of recombinant cells in the mouse pancreas revealed by in situ fluorescence imaging.

Applications of fluorescence for detecting rare sequence rearrangements in vivo.

Open access to research is in the public interest.

DNA double-strand break repair: from mechanistic understanding to cancer treatment.

Three-dimensional tissue cytometer based on high-speed multiphoton microscopy.

Tissue-specific differences in the accumulation of sequence rearrangements with age.

Integrated one- and two-photon imaging platform reveals clonal expansion as a major driver of mutation load.

Quantitative morphometric measurements using site selective image cytometry of intact tissue.

Multiscale structural analysis of mouse lingual myoarchitecture employing diffusion spectrum magnetic resonance imaging and multiphoton microscopy.

Investigation of the effects of aging on homologous recombination in long-term bone marrow cultures.

Development and characterization of a novel variable low dose-rate irradiator for in vivo mouse studies.

Single cell trapping and DNA damage analysis using microwell arrays.

The flap about ATM & MRE11.

Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines.

p53 null fluorescent yellow direct repeat (FYDR) mice have normal levels of homologous recombination.

XRCC1 and base excision repair balance in response to nitric oxide.

Major shifts in the spatio-temporal distribution of lung antioxidant enzymes during influenza pneumonia.

Integrated molecular analysis indicates undetectable change in DNA damage in mice after continuous irradiation at ~ 400-fold natural background radiation.

Genotoxicity of 2,6- and 3,5-dimethylaniline in cultured mammalian cells: the role of reactive oxygen species.

Neutrophils infected with highly virulent influenza H3N2 virus exhibit augmented early cell death and rapid induction of type I interferon signaling pathways.

Peptide targeting and imaging of damaged lung tissue in influenza-infected mice.

Single-cell microarray enables high-throughput evaluation of DNA double-strand breaks and DNA repair inhibitors.

Building on the past, shaping the future: the Environmental Mutagenesis and Genomics Society.

Standard fluorescent imaging of live cells is highly genotoxic.

Investigating the efficacy of pamidronate, a chemical inhibitor of farnesyl pyrophosphate synthase, in the inhibition of influenza virus infection in vitro and in vivo.

Molecular analysis of serum and bronchoalveolar lavage in a mouse model of influenza reveals markers of disease severity that can be clinically useful in humans.

High-throughput screening platform for engineered nanoparticle-mediated genotoxicity using CometChip technology.

Rosa26-GFP direct repeat (RaDR-GFP) mice reveal tissue- and age-dependence of homologous recombination in mammals in vivo.

Cytoplasmic and nuclear toxicity of 3,5-dimethylaminophenol and potential protection by selenocompounds.

Micro-RNAs in regenerating lungs: an integrative systems biology analysis of murine influenza pneumonia.

DNA glycosylase activity and cell proliferation are key factors in modulating homologous recombination in vivo.