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Department of Molecular Pharmacology & Experimental Therapeutics
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Can an in silico drug-target search method be used to probe potential mechanisms of medicinal plant ingredients?
Natural product reports Aug, 2003 | Pubmed ID: 12964838
Effect of selection of molecular descriptors on the prediction of blood-brain barrier penetrating and nonpenetrating agents by statistical learning methods.
Journal of chemical information and modeling Sep-Oct, 2005 | Pubmed ID: 16180914
Computer prediction of allergen proteins from sequence-derived protein structural and physicochemical properties.
Molecular immunology Jan, 2007 | Pubmed ID: 16563508
Are herb-pairs of traditional Chinese medicine distinguishable from others? Pattern analysis and artificial intelligence classification study of traditionally defined herbal properties.
Journal of ethnopharmacology May, 2007 | Pubmed ID: 17267151
AAIR: antibody antigen information resource.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2007 | Pubmed ID: 17404245
Simulation of the regulation of EGFR endocytosis and EGFR-ERK signaling by endophilin-mediated RhoA-EGFR crosstalk.
FEBS letters Jun, 2008 | Pubmed ID: 18505685
Simulation of crosstalk between small GTPase RhoA and EGFR-ERK signaling pathway via MEKK1.
Bioinformatics (Oxford, England) Feb, 2009 | Pubmed ID: 19074159
Pathway sensitivity analysis for detecting pro-proliferation activities of oncogenes and tumor suppressors of epidermal growth factor receptor-extracellular signal-regulated protein kinase pathway at altered protein levels.
Cancer Sep, 2009 | Pubmed ID: 19551902
Comparative transcriptome analyses revealed conserved biological and transcription factor target modules between the zebrafish and human tumors.
Zebrafish Dec, 2009 | Pubmed ID: 19916844
Mercury-induced hepatotoxicity in zebrafish: in vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation.
BMC genomics , 2010 | Pubmed ID: 20353558
Incorporating zebrafish omics into chemical biology and toxicology.
Zebrafish Mar, 2010 | Pubmed ID: 20384484
Liver X receptor agonist T0901317 induced liver perturbation in zebrafish: histological, gene set enrichment and expression analyses.
Biochimica et biophysica acta Jan, 2012 | Pubmed ID: 22047996
Existence of inverted profile in chemically responsive molecular pathways in the zebrafish liver.
PloS one , 2011 | Pubmed ID: 22140468
Toxicogenomic and phenotypic analyses of bisphenol-A early-life exposure toxicity in zebrafish.
PloS one , 2011 | Pubmed ID: 22194820
Metabolic network analysis revealed distinct routes of deletion effects between essential and non-essential genes.
Molecular bioSystems Jan, 2012 | Pubmed ID: 22278128
Toxicogenomic analysis suggests chemical-induced sexual dimorphism in the expression of metabolic genes in zebrafish liver.
PloS one , 2012 | Pubmed ID: 23272195
Inverted expression profiles of sex-biased genes in response to toxicant perturbations and diseases.
PloS one , 2013 | Pubmed ID: 23457601
Molecular insights into 4-nitrophenol-induced hepatotoxicity in zebrafish: transcriptomic, histological and targeted gene expression analyses.
Biochimica et biophysica acta Oct, 2013 | Pubmed ID: 23791553
The evolutionary strata of DARPP-32 tail implicates hierarchical functional expansion in higher vertebrates.
Journal of biosciences Jun, 2014 | Pubmed ID: 24845512
Mayo Clinic College of Medicine, Center for Individualized Medicine
Choong Yong Ung1,
Feng Guo2,
Xiaoling Zhang3,
Zhihui Zhu3,
Shizhen Zhu1,3
1Department of Molecular Pharmacology & Experimental Therapeutics, Mayo Clinic College of Medicine, Center for Individualized Medicine,
2, Tufts University School of Medicine,
3Department of Biochemistry and Molecular Biology, Mayo Clinic
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