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Charles C. Gates Regenerative Medicine and Stem Cell Biology Program,
Department of Medicine,
Webb Waring Institute
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Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2002 | Pubmed ID: 11891296
Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2003 | Pubmed ID: 12646605
Peripheral CD4loCD40+ auto-aggressive T cell expansion during insulin-dependent diabetes mellitus.
European journal of immunology May, 2004 | Pubmed ID: 15114683
Re-shaping the T cell repertoire: TCR editing and TCR revision for good and for bad.
Clinical immunology (Orlando, Fla.) Apr, 2007 | Pubmed ID: 16990051
A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes.
Clinical immunology (Orlando, Fla.) Aug, 2007 | Pubmed ID: 17560173
An analytical workflow for investigating cytokine profiles.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Apr, 2008 | Pubmed ID: 18163472
High distribution of CD40 and TRAF2 in Th40 T cell rafts leads to preferential survival of this auto-aggressive population in autoimmunity.
PloS one , 2008 | Pubmed ID: 18446238
Disruption of the homeostatic balance between autoaggressive (CD4+CD40+) and regulatory (CD4+CD25+FoxP3+) T cells promotes diabetes.
Journal of leukocyte biology Aug, 2008 | Pubmed ID: 18469093
CD40 on NOD CD4 T cells contributes to their activation and pathogenicity.
Journal of autoimmunity Dec, 2008 | Pubmed ID: 18951762
CD40 glycoforms and TNF-receptors 1 and 2 in the formation of CD40 receptor(s) in autoimmunity.
Molecular immunology Aug, 2010 | Pubmed ID: 20646763
The pathology of bleomycin-induced fibrosis is associated with loss of resident lung mesenchymal stem cells that regulate effector T-cell proliferation.
Stem cells (Dayton, Ohio) Apr, 2011 | Pubmed ID: 21312316
CD40 engagement of CD4(+) CD40(+) T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance.
European journal of immunology Feb, 2012 | Pubmed ID: 22105491
University of Colorado Denver
Kelsey S. Chow1,2,
DuHyun Jun1,2,
Karen M. Helm3,
David H. Wagner1,2,4,
Susan M. Majka1,2,3
1Charles C. Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado Denver,
2Department of Medicine, University of Colorado Denver,
3Cancer Center, University of Colorado Denver,
4Webb Waring Institute, University of Colorado Denver
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