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Department of Biochemistry and Molecular Biology
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The SecYEG preprotein translocation channel is a conformationally dynamic and dimeric structure.
The EMBO journal Mar, 2002 | Pubmed ID: 11867527
Binding, activation and dissociation of the dimeric SecA ATPase at the dimeric SecYEG translocase.
The EMBO journal Sep, 2003 | Pubmed ID: 12941690
Break on through to the other side--the Sec translocon.
Trends in biochemical sciences May, 2004 | Pubmed ID: 15130556
The bacterial protein-translocation complex: SecYEG dimers associate with one or two SecA molecules.
Journal of molecular biology Jul, 2004 | Pubmed ID: 15210351
Investigating the SecY plug movement at the SecYEG translocation channel.
The EMBO journal Oct, 2005 | Pubmed ID: 16148946
Deregulation of the SecYEG translocation channel upon removal of the plug domain.
The Journal of biological chemistry Jan, 2007 | Pubmed ID: 17092931
Nanodiscs unravel the interaction between the SecYEG channel and its cytosolic partner SecA.
The EMBO journal Apr, 2007 | Pubmed ID: 17396152
Cell biology: fraternal twins.
Nature Apr, 2007 | Pubmed ID: 17429388
Structure and function of the bacterial Sec translocon.
Molecular membrane biology Sep-Dec, 2007 | Pubmed ID: 17710643
Structure, binding, and activity of Syd, a SecY-interacting protein.
The Journal of biological chemistry Mar, 2009 | Pubmed ID: 19139097
The SecY complex forms a channel capable of ionic discrimination.
EMBO reports Jul, 2009 | Pubmed ID: 19483671
Modulation of the SecY channel permeability by pore mutations and trivalent cations.
Channels (Austin, Tex.) Mar-Apr, 2010 | Pubmed ID: 20026911
Reconstitution of the SecY translocon in nanodiscs.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20419409
The action of cardiolipin on the bacterial translocon.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2010 | Pubmed ID: 20479269
The SecY complex: conducting the orchestra of protein translocation.
Trends in cell biology Sep, 2011 | Pubmed ID: 21632250
Nanodiscs and SILAC-Based Mass Spectrometry to Identify a Membrane Protein Interactome.
Journal of proteome research Feb, 2012 | Pubmed ID: 22129326
Two copies of the SecY channel and acidic lipids are necessary to activate the SecA translocation ATPase.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2012 | Pubmed ID: 22378651
Structure-activity analysis of niclosamide reveals potential role for cytoplasmic pH in control of mammalian target of rapamycin complex 1 (mTORC1) signaling.
The Journal of biological chemistry May, 2012 | Pubmed ID: 22474287
Discovery of an auto-regulation mechanism for the maltose ABC transporter MalFGK2.
PloS one , 2012 | Pubmed ID: 22529943
University of British Columbia
Huan Bao1,
Franck Duong1,
Catherine S. Chan1
1Department of Biochemistry and Molecular Biology, University of British Columbia
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