Centre of Excellence for Alzheimer's Disease Research and Care,
School of Medical Sciences,
Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical sciences
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Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease.
Neurobiology of aging Sep, 2003 | Pubmed ID: 12885573
Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression.
Journal of neurochemistry Feb, 2004 | Pubmed ID: 14720205
Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition.
The Journal of biological chemistry May, 2004 | Pubmed ID: 14871891
The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught?
Pharmacological research : the official journal of the Italian Pharmacological Society Oct, 2004 | Pubmed ID: 15304237
Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells.
Alzheimer disease and associated disorders Oct-Dec, 2004 | Pubmed ID: 15592142
Plasma Abeta42 correlates positively with increased body fat in healthy individuals.
Journal of Alzheimer's disease : JAD Dec, 2005 | Pubmed ID: 16340084
The role of gonadotropins in Alzheimer's disease: potential neurodegenerative mechanisms.
Endocrine Apr, 2006 | Pubmed ID: 16785601
The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid.
Neurochemical research Apr-May, 2007 | Pubmed ID: 16944319
Reproductive hormones modulate oxidative stress in Alzheimer's disease.
Antioxidants & redox signaling Nov-Dec, 2006 | Pubmed ID: 17034349
Interference with splicing of Presenilin transcripts has potent dominant negative effects on Presenilin activity.
Human molecular genetics Feb, 2008 | Pubmed ID: 17981814
Research criteria for the diagnosis of Alzheimer's disease: genetic risk factors, blood biomarkers and olfactory dysfunction.
International psychogeriatrics / IPA Aug, 2008 | Pubmed ID: 18416874
Gonadotropins and cognition in older women.
Journal of Alzheimer's disease : JAD Apr, 2008 | Pubmed ID: 18430994
Luteinizing hormone levels are positively correlated with plasma amyloid-beta protein levels in elderly men.
Journal of Alzheimer's disease : JAD Jun, 2008 | Pubmed ID: 18560131
Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease.
Journal of neuroinflammation , 2008 | Pubmed ID: 18715507
Distinct effects of testosterone on plasma and cerebrospinal fluid amyloid-beta levels.
Journal of Alzheimer's disease : JAD Sep, 2008 | Pubmed ID: 18780973
Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity.
International journal of clinical and experimental medicine , 2008 | Pubmed ID: 19079689
Independent and cooperative action of Psen2 with Psen1 in zebrafish embryos.
Experimental cell research Oct, 2009 | Pubmed ID: 19563801
Predicting memory decline as a risk factor for Alzheimer's disease in older post-menopausal women: quod erat demonstrandum?
International psychogeriatrics / IPA Mar, 2010 | Pubmed ID: 19814842
The structure and function of Alzheimer's gamma secretase enzyme complex.
Critical reviews in clinical laboratory sciences , 2009 | Pubmed ID: 19958215
Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease.
Journal of neurochemistry Dec, 2009 | Pubmed ID: 20050287
A zebrafish melanophore model of amyloid beta toxicity.
Zebrafish Jun, 2010 | Pubmed ID: 20515319
Zebrafish as a tool in Alzheimer's disease research.
Biochimica et biophysica acta Mar, 2011 | Pubmed ID: 20920580
New lexicon and criteria for the diagnosis of Alzheimer's disease.
Lancet neurology Apr, 2011 | Pubmed ID: 21435594
Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study.
Neuropsychologia Jul, 2011 | Pubmed ID: 21529702
The dynamics of CD147 in Alzheimer's disease development and pathology.
Journal of Alzheimer's disease : JAD , 2011 | Pubmed ID: 21694447
Direct exposure of guinea pig CNS to human luteinizing hormone increases cerebrospinal fluid and cerebral beta amyloid levels.
Neuroendocrinology , 2011 | Pubmed ID: 21985789
Evaluation of color preference in zebrafish for learning and memory.
Journal of Alzheimer's disease : JAD , 2012 | Pubmed ID: 22008261
Latrepirdine (Dimebon™) Enhances Autophagy and Reduces Intracellular GFP-Aβ42 Levels in Yeast.
Journal of Alzheimer's disease : JAD Jan, 2012 | Pubmed ID: 22903131
Avdesh Avdesh*,1,2,
Mengqi Chen*,1,3,
Mathew T. Martin-Iverson1,2,4,
Alinda Mondal1,3,
Daniel Ong1,
Stephanie Rainey-Smith1,3,
Kevin Taddei1,3,
Michael Lardelli5,
David M. Groth6,
Giuseppe Verdile1,3,
Ralph N. Martins1,2,3,7
1Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical sciences, Edith Cowan University,
2Centre for Clinical Research in Neuropsychiatry, Graylands Hospital, University of Western Australia,
3, McCusker Alzheimer's Research foundation,
4School of Medicine and Pharmacology, University of Western Australia ,
5Department of Molecular and Biomedical Sciences, University of Adelaide,
6School of Biomedical Sciences, Curtin University of Technology,
7School of Psychiatry and Clinical Neurosciences, University of Western Australia
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