Guruprasad Giridharan

Characterization of an adult mock circulation for testing cardiac support devices.

Left ventricular and myocardial perfusion responses to volume unloading and afterload reduction in a computer simulation.

Ascending aorta outflow graft location and pulsatile ventricular assist provide optimal hemodynamic support in an adult mock circulation.

Predicted hemodynamic benefits of counterpulsation therapy using a superficial surgical approach.

Physiological control of blood pumps using intrinsic pump parameters: a computer simulation study.

A computer model of the pediatric circulatory system for testing pediatric assist devices.

Vascular pulsatility in patients with a pulsatile- or continuous-flow ventricular assist device.

Quantification of pulsatility as a function of vascular input impedance: an in vitro study.

Effect of continuous and pulsatile flow left ventricular assist on pulsatility in a pediatric animal model of left ventricular dysfunction: pilot observations.

The influence of mock circulation input impedance on valve acceleration during in vitro cardiac device testing.

Acute hemodynamic efficacy of a 32-ml subcutaneous counterpulsation device in a calf model of diminished cardiac function.

Human, bovine and porcine systematic vascular input impedances are not equivalent: implications for device testing and xenotransplantation in heart failure.

Intraoperative evaluation of the HeartMate II flow estimator.

Novel J stents reduce the risk of embolic stroke in vitro.

Discerning aortic waves during intra-aortic balloon pumping and their relation to benefits of counterpulsation in humans.

Microfluidic cardiac circulation model (microCCM) for functional cardiomyocyte studies.

Increase in circadian variation after continuous-flow ventricular assist device implantation.

A novel subcutaneous counterpulsation device: acute hemodynamic efficacy during pharmacologically induced hypertension, hypotension, and heart failure.

Cavopulmonary assist for the univentricular Fontan circulation: von Kármán viscous impeller pump.

Hemodynamic responses to continuous versus pulsatile mechanical unloading of the failing left ventricle.

Microfluidic cardiac cell culture model (μCCCM).

Bovine model of doxorubicin-induced cardiomyopathy.

Transapical miniaturized ventricular assist device: design and initial testing.

Endothelial cell culture model for replication of physiological profiles of pressure, flow, stretch, and shear stress in vitro.

Cavopulmonary assist: (em)powering the univentricular fontan circulation.

Blood trauma testing for mechanical circulatory support devices.

Accurate automatic analysis of cardiac cine images.

Endothelial cell culture model of carotid artery atherosclerosis.

Performance evaluation of a pediatric viscous impeller pump for Fontan cavopulmonary assist.

Mechanism of myocardial ischemia with an anomalous left coronary artery from the right sinus of Valsalva.

Counterpulsation with symphony prevents retrograde carotid, aortic, and coronary flows observed with intra-aortic balloon pump support.

Control strategies for afterload reduction with an artificial vasculature device.

Microfluidic endothelial cell culture model to replicate disturbed flow conditions seen in atherosclerosis susceptible regions.

Blood trauma testing of CentriMag and RotaFlow centrifugal flow devices: a pilot study.

Miniaturization of mechanical circulatory support systems.

Defining pulsatility during continuous-flow ventricular assist device support.

Benefits of aggressive medical management in a bovine model of chronic ischemic heart failure.

Flow modulation algorithms for intra-aortic rotary blood pumps to minimize coronary steal.

Rotary pumps and diminished pulsatility: do we need a pulse?

Fault detection in rotary blood pumps using motor speed response.

Bovine model of chronic ischemic cardiomyopathy: implications for ventricular assist device research.

Cardiac cell culture model as a left ventricle mimic for cardiac tissue generation.

Large animal models for left ventricular assist device research and development.

Early feasibility testing and engineering development of the transapical approach for the HeartWare MVAD ventricular assist system.

Do axial-flow LVADs unload better than centrifugal-flow LVADs?

Cavopulmonary assist for the failing Fontan circulation: impact of ventricular function on mechanical support strategy.

Development of an extracellular matrix delivery system for effective intramyocardial injection in ischemic tissue.

Early feasibility testing and engineering development of a sutureless beating heart connector for left ventricular assist devices.

Rotary blood pump control strategy for preventing left ventricular suction.

Suction prevention and physiologic control of continuous flow left ventricular assist devices using intrinsic pump parameters.

Feasibility study of particulate extracellular matrix (P-ECM) and left ventricular assist device (HVAD) therapy in chronic ischemic heart failure bovine model.

Rotary pump speed modulation for generating pulsatile flow and phasic left ventricular volume unloading in a bovine model of chronic ischemic heart failure.

Effects of physiologic mechanical stimulation on embryonic chick cardiomyocytes using a microfluidic cardiac cell culture model.

Hemodynamic changes and retrograde flow in LVAD failure.

Left ventricular volume unloading with axial and centrifugal rotary blood pumps.

Feasibility Study of Pulsatile Left Ventricular Assist Device for Prolonged Ex Vivo Lung Perfusion.

Feasibility of Pump Speed Modulation for Restoring Vascular Pulsatility with Rotary Blood Pumps.

Evaluation of the effect of diminished pulsatility as seen in continuous flow ventricular assist devices on arterial endothelial cell phenotype and function.

Efficacy of Subcutaneous Electrocardiogram Leads for Synchronous Timing During Chronic Counterpulsation Therapy.

Continuous-Flow Left Ventricular Assist Device Support Improves Myocardial Supply:Demand in Chronic Heart Failure.

Hemodynamic Benefits of Counterpulsation, Implantable, Percutaneous, and Intraaortic Rotary Blood Pumps: An In-Silico and In Vitro Study.

Flow features and device-induced blood trauma in CF-VADs under a pulsatile blood flow condition: A CFD comparative study.

Sensor-Based Physiologic Control Strategy for Biventricular Support with Rotary Blood Pumps.

Shear stress and blood trauma under constant and pulse-modulated speed CF-VAD operations: CFD analysis of the HVAD.

Evaluation of flow-modulation approaches in ventricular assist devices using an in-vitro endothelial cell culture model.

Physiological Biomimetic Culture System for Pig and Human Heart Slices.

A Novel Framework for Early Detection of Hypertension using Magnetic Resonance Angiography.

Cavopulmonary assist: Long-term reversal of the Fontan paradox.

A novel computer-aided diagnosis system for the early detection of hypertension based on cerebrovascular alterations.

A Multimodal Computer-Aided Diagnostic System for Precise Identification of Renal Allograft Rejection: Preliminary Results.