David Geffen School of Medicine
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Activation of CD8 T cells induces expression of CD4, which functions as a chemotactic receptor.
Blood Jan, 2002 | Pubmed ID: 11756173
Effect of latent human immunodeficiency virus infection on cell surface phenotype.
Journal of virology Feb, 2002 | Pubmed ID: 11799162
Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2002 | Pubmed ID: 11854483
Cocaine enhances human immunodeficiency virus replication in a model of severe combined immunodeficient mice implanted with human peripheral blood leukocytes.
The Journal of infectious diseases Mar, 2002 | Pubmed ID: 11865430
Effects of prostratin on T-cell activation and human immunodeficiency virus latency.
Journal of virology Aug, 2002 | Pubmed ID: 12134017
Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype.
Journal of virology Dec, 2002 | Pubmed ID: 12438635
HIV type 1 infection alters cytokine mRNA expression in thymus.
AIDS research and human retroviruses Jan, 2003 | Pubmed ID: 12581511
Human immunodeficiency virus type 1 infection and replication in normal human oral keratinocytes.
Journal of virology Mar, 2003 | Pubmed ID: 12610122
HIV-1 infection in peripheral blood lymphocytes (PBLs) exposed to alcohol.
Virology Mar, 2003 | Pubmed ID: 12667812
Molecular characterization, reactivation, and depletion of latent HIV.
Immunity Sep, 2003 | Pubmed ID: 14499116
Controlling false-negative errors in microarray differential expression analysis: a PRIM approach.
Bioinformatics (Oxford, England) Sep, 2003 | Pubmed ID: 14512352
Identification of T cell-signaling pathways that stimulate latent HIV in primary cells.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2003 | Pubmed ID: 14569007
Psychological risk factors for HIV pathogenesis: mediation by the autonomic nervous system.
Biological psychiatry Dec, 2003 | Pubmed ID: 14675810
Impacts of epitope expression kinetics and class I downregulation on the antiviral activity of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes.
Journal of virology Jan, 2004 | Pubmed ID: 14694087
Public health. A sound rationale needed for phase III HIV-1 vaccine trials.
Science (New York, N.Y.) Jan, 2004 | Pubmed ID: 14726576
The CCR5 and CXCR4 coreceptors--central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection.
AIDS research and human retroviruses Jan, 2004 | Pubmed ID: 15000703
Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients.
Human gene therapy Mar, 2004 | Pubmed ID: 15018734
Stress-induced enhancement of NF-kappaB DNA-binding in the peripheral blood leukocyte pool: effects of lymphocyte redistribution.
Brain, behavior, and immunity May, 2004 | Pubmed ID: 15050650
CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2004 | Pubmed ID: 15173593
Alcohol enhances HIV type 1 infection in normal human oral keratinocytes by up-regulating cell-surface CXCR4 coreceptor.
AIDS research and human retroviruses May, 2004 | Pubmed ID: 15186526
Expression-based monitoring of transcription factor activity: the TELiS database.
Bioinformatics (Oxford, England) Mar, 2005 | Pubmed ID: 15374858
The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2005 | Pubmed ID: 15731353
Prostratin and bortezomib are novel inducers of latent Kaposi's sarcoma-associated herpesvirus.
Antiviral therapy , 2005 | Pubmed ID: 16218174
beta-Adrenoreceptors reactivate Kaposi's sarcoma-associated herpesvirus lytic replication via PKA-dependent control of viral RTA.
Journal of virology Nov, 2005 | Pubmed ID: 16227274
Rapid size dependent deletion of foreign gene sequences inserted into attenuated HIV-1 upon infection in vivo: implications for vaccine development.
Current HIV research Oct, 2005 | Pubmed ID: 16250884
Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research Nov, 2005 | Pubmed ID: 16318584
PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2006 | Pubmed ID: 16373498
Rapid expression of human immunodeficiency virus following activation of latently infected cells.
Journal of virology Feb, 2006 | Pubmed ID: 16415036
T lineage differentiation from human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2006 | Pubmed ID: 16844782
CD4 expression on activated NK cells: ligation of CD4 induces cytokine expression and cell migration.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2006 | Pubmed ID: 16951326
A plea for justice for jailed medical workers.
Science (New York, N.Y.) Nov, 2006 | Pubmed ID: 17062652
Immediate activation fails to rescue efficient human immunodeficiency virus replication in quiescent CD4+ T cells.
Journal of virology Apr, 2007 | Pubmed ID: 17229711
Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques.
Journal of immunology (Baltimore, Md. : 1950) Mar, 2007 | Pubmed ID: 17339444
Human immunodeficiency virus bearing a disrupted central DNA flap is pathogenic in vivo.
Journal of virology Jun, 2007 | Pubmed ID: 17392373
Primary cell model for activation-inducible human immunodeficiency virus.
Journal of virology Jul, 2007 | Pubmed ID: 17475639
Generation of T lineage cells from human embryonic stem cells in a feeder free system.
Stem cells (Dayton, Ohio) Jan, 2009 | Pubmed ID: 18974209
Eradication of HIV: current challenges and new directions.
The Journal of antimicrobial chemotherapy Jan, 2009 | Pubmed ID: 18984648
Short communication: Activating stimuli enhance immunotoxin-mediated killing of HIV-infected macrophages.
AIDS research and human retroviruses Nov, 2008 | Pubmed ID: 19000022
A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors.
Genes & development Nov, 2008 | Pubmed ID: 19056892
Differentially stimulated CD4+ T cells display altered human immunodeficiency virus infection kinetics: implications for the efficacy of antiviral agents.
Journal of virology Apr, 2009 | Pubmed ID: 19129455
Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells.
Nature medicine Mar, 2009 | Pubmed ID: 19219022
A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors.
Stem cells (Dayton, Ohio) Jan, 2009 | Pubmed ID: 19224508
CD4+ NK cells can be productively infected with HIV, leading to downregulation of CD4 expression and changes in function.
Virology Apr, 2009 | Pubmed ID: 19251297
Human immunodeficiency virus integration efficiency and site selection in quiescent CD4+ T cells.
Journal of virology Jun, 2009 | Pubmed ID: 19369341
Animal models of HIV-1 latency and persistence.
Current opinion in HIV and AIDS Mar, 2006 | Pubmed ID: 19372792
Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.
PloS one , 2009 | Pubmed ID: 19997617
A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model.
Blood Feb, 2010 | Pubmed ID: 20018916
Differential expression and interaction of host factors augment HIV-1 gene expression in neonatal mononuclear cells.
Virology Apr, 2010 | Pubmed ID: 20138641
Macrophage differentiation from embryoid bodies derived from human embryonic stem cells.
Journal of stem cells , 2009 | Pubmed ID: 20498689
Gene expression and transcription factor profiling reveal inhibition of transcription factor cAMP-response element-binding protein by gamma-herpesvirus replication and transcription activator.
The Journal of biological chemistry Aug, 2010 | Pubmed ID: 20516076
CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes.
PloS one , 2010 | Pubmed ID: 20625427
Quiescent T cells and HIV: an unresolved relationship.
Immunologic research Dec, 2010 | Pubmed ID: 20725862
Female human iPSCs retain an inactive X chromosome.
Cell stem cell Sep, 2010 | Pubmed ID: 20727844
Stem cell-based approaches to treating HIV infection.
Current opinion in HIV and AIDS Jan, 2011 | Pubmed ID: 21242896
Establishment and maintenance of HIV latency: model systems and opportunities for intervention.
Future virology Jan, 2010 | Pubmed ID: 21318097
Activation of latent HIV using drug-loaded nanoparticles.
PloS one , 2011 | Pubmed ID: 21483687
Single mutations in HIV integrase confer high-level resistance to raltegravir in primary human macrophages.
Antimicrobial agents and chemotherapy Aug, 2011 | Pubmed ID: 21628534
Phase I/II Clinical Trials Using Gene-Modified Adult Hematopoietic Stem Cells for HIV: Lessons Learnt.
Stem cells international , 2011 | Pubmed ID: 21716651
HIV latency is influenced by regions of the viral genome outside of the long terminal repeats and regulatory genes.
Virology Sep, 2011 | Pubmed ID: 21777932
HIV latency in the humanized BLT mouse.
Journal of virology Jan, 2012 | Pubmed ID: 22072769
Genome-wide binding map of the HIV-1 Tat protein to the human genome.
PloS one , 2011 | Pubmed ID: 22073215
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2011 | Pubmed ID: 22123951
In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells.
PLoS pathogens , 2012 | Pubmed ID: 22511873
Virological evidence supporting the use of raltegravir in HIV post-exposure prophylaxis regimens.
Antiviral therapy , 2012 | Pubmed ID: 22820096
Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro.
Nature chemistry Sep, 2012 | Pubmed ID: 22914190
From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols.
Stem cells translational medicine Jan, 2012 | Pubmed ID: 23197638
Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.
Immunity Jan, 2013 | Pubmed ID: 23273844
Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression.
Molecular therapy : the journal of the American Society of Gene Therapy May, 2013 | Pubmed ID: 23481324
HIV restriction in quiescent CD4⁺ T cells.
Retrovirology , 2013 | Pubmed ID: 23557201
HIV/AIDS eradication.
Bioorganic & medicinal chemistry letters Jul, 2013 | Pubmed ID: 23735743
Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2013 | Pubmed ID: 23812750
Cocaine exposure enhances permissiveness of quiescent T cells to HIV infection.
Journal of leukocyte biology Oct, 2013 | Pubmed ID: 23817564
HIV-1 infection of hematopoietic progenitor cells in vivo in humanized mice.
Blood Sep, 2013 | Pubmed ID: 23886835
Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status.
Stem cell research & therapy Jul, 2013 | Pubmed ID: 23890092
Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2014 | Pubmed ID: 24634374
CD4 ligation on human blood monocytes triggers macrophage differentiation and enhances HIV infection.
Journal of virology Sep, 2014 | Pubmed ID: 24942581
Bioengineered vaults: self-assembling protein shell-lipophilic core nanoparticles for drug delivery.
ACS nano Aug, 2014 | Pubmed ID: 25061969
Neutralizing the HIV reservoir.
Cell Aug, 2014 | Pubmed ID: 25171398
Double trouble: HIV latency and CTL escape.
Cell host & microbe Feb, 2015 | Pubmed ID: 25674977
Studies of retroviral infection in humanized mice.
Virology May, 2015 | Pubmed ID: 25680625
RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice.
Molecular therapy. Nucleic acids , 2015 | Pubmed ID: 25689223
Cocaine exposure impairs multilineage hematopoiesis of human hematopoietic progenitor cells mediated by the sigma-1 receptor [corrected].
Scientific reports , 2015 | Pubmed ID: 25728014
Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs.
Cell stem cell Apr, 2015 | Pubmed ID: 25772073
Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.
The Journal of clinical investigation May, 2015 | Pubmed ID: 25822024
HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells.
Molecular therapy : the journal of the American Society of Gene Therapy Aug, 2015 | Pubmed ID: 26050990
Cocaine-mediated impact on HIV infection in humanized BLT mice.
Scientific reports , 2015 | Pubmed ID: 26084721
Corrigendum: Cocaine exposure impairs multilineage hematopoiesis of human hematopoietic progenitor cells mediated by the sigma-1 receptor.
Scientific reports , 2015 | Pubmed ID: 26166708
Disruption of Type I Interferon Induction by HIV Infection of T Cells.
PloS one , 2015 | Pubmed ID: 26375588
Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary.
AIDS research and human retroviruses Feb, 2016 | Pubmed ID: 26670361
A Single CRISPR-Cas9 Deletion Strategy that Targets the Majority of DMD Patients Restores Dystrophin Function in hiPSC-Derived Muscle Cells.
Cell stem cell Apr, 2016 | Pubmed ID: 26877224
Medial HOXA genes demarcate haematopoietic stem cell fate during human development.
Nature cell biology Jun, 2016 | Pubmed ID: 27183470
HIV-1-Specific Chimeric Antigen Receptors Based on Broadly-Neutralizing Antibodies.
Journal of virology May, 2016 | Pubmed ID: 27226366
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