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Institute of Biochemistry
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SWAP-70-deficient mast cells are impaired in development and IgE-mediated degranulation.
European journal of immunology Apr, 2002 | Pubmed ID: 11920580
A complex of the Srb8, -9, -10, and -11 transcriptional regulatory proteins from yeast.
The Journal of biological chemistry Nov, 2002 | Pubmed ID: 12200444
Association of the Mediator complex with enhancers of active genes.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2003 | Pubmed ID: 14623974
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Molecular cell Jun, 2004 | Pubmed ID: 15175151
The sphingosine-1-phosphate (S1P) lysophospholipid receptor S1P3 regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization.
The Journal of experimental medicine Dec, 2004 | Pubmed ID: 15583019
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes.
Molecular and cellular biology Dec, 2005 | Pubmed ID: 16287852
The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2006 | Pubmed ID: 17132730
ETO, but not leukemogenic fusion protein AML1/ETO, augments RBP-Jkappa/SHARP-mediated repression of notch target genes.
Molecular and cellular biology May, 2008 | Pubmed ID: 18332109
Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex.
Genes & development Mar, 2010 | Pubmed ID: 20231316
Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2010 | Pubmed ID: 21098667
RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J.
The EMBO journal Jan, 2011 | Pubmed ID: 21102556
Interactions between subunits of the Mediator complex with gene-specific transcription factors.
Seminars in cell & developmental biology Sep, 2011 | Pubmed ID: 21839847
Essential role of Mediator subunit Med1 in invariant natural killer T-cell development.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2011 | Pubmed ID: 21949387
Fine-tuning of the intracellular canonical Notch signaling pathway.
Cell cycle (Georgetown, Tex.) Jan, 2012 | Pubmed ID: 22223095
RNA helicase Ddx5 and the noncoding RNA SRA act as coactivators in the Notch signaling pathway.
Biochimica et biophysica acta May, 2013 | Pubmed ID: 23396200
Keeping notch target genes off: a CSL corepressor caught in the act.
Structure (London, England : 1993) Jan, 2014 | Pubmed ID: 24411574
The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.
Science signaling Mar, 2014 | Pubmed ID: 24643801
Probing the epigenetic status at Notch target genes.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 25053496
Site-specific methylation of Notch1 controls the amplitude and duration of the Notch1 response.
Science signaling Mar, 2015 | Pubmed ID: 25805888
The Notch intracellular domain integrates signals from Wnt, Hedgehog, TGFβ/BMP and hypoxia pathways.
Biochimica et biophysica acta Feb, 2016 | Pubmed ID: 26592459
Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination.
The Journal of experimental medicine Mar, 2016 | Pubmed ID: 26903242
A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes.
Nucleic acids research Jun, 2016 | Pubmed ID: 26912830
Setting the Stage for Notch: The Drosophila Su(H)-Hairless Repressor Complex.
PLoS biology Jul, 2016 | Pubmed ID: 27458807
Host-derived extracellular RNA promotes adhesion of Streptococcus pneumoniae to endothelial and epithelial cells.
Scientific reports Nov, 2016 | Pubmed ID: 27892961
Dynamic chromatin regulation at Notch target genes.
Transcription Jan, 2017 | Pubmed ID: 28027012
University of Giessen
Benedetto Daniele Giaimo1,
Francesca Ferrante1,
Tilman Borggrefe1
1Institute of Biochemistry, University of Giessen
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