Department of Ophthalmology,
Shanghai General Hospital,
Department of Ophthalmology, Shanghai General Hospital
Xiaodong Sun has not added Biography.
If you are Xiaodong Sun and would like to personalize this page please email our Author Liaison for assistance.
A potential therapeutic strategy for inhibition of ocular neovascularization with a new endogenous protein: rhEDI-8t.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Sep, 2011 | Pubmed ID: 21881847
Late adult onset optic pathway astrocytoma.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia Nov, 2013 | Pubmed ID: 23790623
Binding pancreaticogastrostomy in laparoscopic central pancreatectomy: a novel technique in laparoscopic pancreatic surgery.
Surgical endoscopy Feb, 2016 | Pubmed ID: 26123326
A2E Suppresses Regulatory Function of RPE Cells in Th1 Cell Differentiation Via Production of IL-1β and Inhibition of PGE2.
Investigative ophthalmology & visual science Dec, 2015 | Pubmed ID: 26641550
Joint Antiangiogenic Effect of ATN-161 and Anti-VEGF Antibody in a Rat Model of Early Wet Age-Related Macular Degeneration.
Molecular pharmaceutics Sep, 2016 | Pubmed ID: 27089240
CHOROIDAL THICKNESS IN UNILATERAL IDIOPATHIC MACULAR HOLE: A Cross-Sectional Study and Meta-Analysis.
Retina (Philadelphia, Pa.) Jan, 2017 | Pubmed ID: 27322947
Resistance to anti-VEGF therapy in neovascular age-related macular degeneration: a comprehensive review.
Drug design, development and therapy , 2016 | Pubmed ID: 27330279
Antiangiogenic Effects of Doxazosin on Experimental Choroidal Neovascularization in Mice.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics , 2017 | Pubmed ID: 27992238
Involvement of XBP1s in Blue Light-Induced A2E-Containing Retinal Pigment Epithelium Cell Death.
Ophthalmic research , 2017 | Pubmed ID: 28099966
MicroRNA Expression Patterns Involved in Amyloid Beta-Induced Retinal Degeneration.
Investigative ophthalmology & visual science Mar, 2017 | Pubmed ID: 28324113
Paravascular abnormalities observed by spectral domain optical coherence tomography are risk factors for retinoschisis in eyes with high myopia.
Acta ophthalmologica Jun, 2018 | Pubmed ID: 29171725
Quantification of Macular Vascular Density Using Optical Coherence Tomography Angiography and Its Relationship with Retinal Thickness in Myopic Eyes of Young Adults.
Journal of ophthalmology , 2017 | Pubmed ID: 29318037
Autophagy activated by SIRT6 regulates Aβ induced inflammatory response in RPEs.
Biochemical and biophysical research communications Feb, 2018 | Pubmed ID: 29402409
Photosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence.
Cell death & disease Feb, 2018 | Pubmed ID: 29415988
Development of a new valid and reliable microsurgical skill assessment scale for ophthalmology residents.
BMC ophthalmology Mar, 2018 | Pubmed ID: 29506509
Choroidal and Retinal Thickness of Highly Myopic Eyes with Early Stage of Myopic Chorioretinopathy: Tessellation.
Journal of ophthalmology , 2018 | Pubmed ID: 29607214
Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation.
Disease models & mechanisms Apr, 2018 | Pubmed ID: 29622551
Inhibition of Mitochondrial Fission Preserves Photoreceptors after Retinal Detachment.
The American journal of pathology Jul, 2018 | Pubmed ID: 29684364
Conbercept for Treatment of Neovascular Age-related Macular Degeneration: Results of the Randomized Phase 3 PHOENIX Study.
American journal of ophthalmology Jan, 2019 | Pubmed ID: 30148987
DNMT1 and Sp1 competitively regulate the expression of BACE1 in A2E-mediated photo-oxidative damage in RPE cells.
Neurochemistry international Dec, 2018 | Pubmed ID: 30273642
Identification of novel PROM1 mutations responsible for autosomal recessive maculopathy with rod-cone dystrophy.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Mar, 2019 | Pubmed ID: 30588538
Modulation of α-adrenoceptor signalling protects photoreceptors after retinal detachment by inhibiting oxidative stress and inflammation.
British journal of pharmacology Mar, 2019 | Pubmed ID: 30588605
UMSC-derived exosomes promote retinal ganglion cells survival in a rat model of optic nerve crush.
Journal of chemical neuroanatomy Mar, 2019 | Pubmed ID: 30639447
Appearance of Polypoidal Lesions in Patients With Polypoidal Choroidal Vasculopathy Using Swept-Source Optical Coherence Tomographic Angiography.
JAMA ophthalmology Jun, 2019 | Pubmed ID: 30998817
Progression and new onset of macular retinoschisis in myopic choroidal neovascularization eyes after Conbercept therapy: a post-hoc analysis.
Eye (London, England) Mar, 2020 | Pubmed ID: 31358922
Complement system and age-related macular degeneration: drugs and challenges.
Drug design, development and therapy , 2019 | Pubmed ID: 31409975
Intraocular VEGF deprivation induces degeneration and fibrogenic response in retina.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Dec, 2019 | Pubmed ID: 31648566
Chitinase-3-Like-1 Promotes M2 Macrophage Differentiation and Induces Choroidal Neovascularization in Neovascular Age-Related Macular Degeneration.
Investigative ophthalmology & visual science Nov, 2019 | Pubmed ID: 31675076
Autophagy activated via GRP78 to alleviate endoplasmic reticulum stress for cell survival in blue light-mediated damage of A2E-laden RPEs.
BMC ophthalmology Dec, 2019 | Pubmed ID: 31823795
Quantitative assessment of the retinal microvasculature and choriocapillaris in myopic patients using swept-source optical coherence tomography angiography.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Jun, 2020 | Pubmed ID: 32144487
Intravitreal Aflibercept versus Laser Photocoagulation in Asian Patients with Diabetic Macular Edema: The VIVID-East Study.
Clinical ophthalmology (Auckland, N.Z.) , 2020 | Pubmed ID: 32210527
Evaluation of the association of macular ganglion cell-inner plexiform layer thickness and myopia in Chinese young adults.
Eye (London, England) Feb, 2021 | Pubmed ID: 32291406
3-Methyladenine Alleviates Experimental Subretinal Fibrosis by Inhibiting Macrophages and M2 Polarization Through the PI3K/Akt Pathway.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Oct, 2020 | Pubmed ID: 32552228
xCT regulates redox homeostasis and promotes photoreceptor survival after retinal detachment.
Free radical biology & medicine Oct, 2020 | Pubmed ID: 32679366
Photoreceptors Degenerate Through Pyroptosis After Experimental Retinal Detachment.
Investigative ophthalmology & visual science Jul, 2020 | Pubmed ID: 32697303
The Efficacy of Conbercept in Polypoidal Choroidal Vasculopathy: A Systematic Review.
Journal of ophthalmology , 2020 | Pubmed ID: 32855818
ROS production and mitochondrial dysfunction driven by PU.1-regulated NOX4-p22 activation in Aβ-induced retinal pigment epithelial cell injury.
Theranostics , 2020 | Pubmed ID: 33052238
Lentiviral delivery of co-packaged Cas9 mRNA and a Vegfa-targeting guide RNA prevents wet age-related macular degeneration in mice.
Nature biomedical engineering Feb, 2021 | Pubmed ID: 33398131
SLC7A11 Reduces Laser-Induced Choroidal Neovascularization by Inhibiting RPE Ferroptosis and VEGF Production.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 33681224
Replacement of polyps with type 1 macular neovascularization in polypoidal choroidal vasculopathy imaged with swept source OCT angiography.
American journal of ophthalmology case reports Jun, 2021 | Pubmed ID: 33796797
Small dome-shaped pigment epithelium detachment in polypoidal choroidal vasculopathy: an under-recognized sign of polypoidal lesions on optical coherence tomography?
Eye (London, England) Apr, 2022 | Pubmed ID: 33833415
Peripapillary Vessel Density in Eyes with Rhegmatogenous Retinal Detachment after Pars Plana Vitrectomy.
Journal of ophthalmology , 2021 | Pubmed ID: 33859835
The Interaction Between Microglia and Macroglia in Glaucoma.
Frontiers in neuroscience , 2021 | Pubmed ID: 34121982
Modeling Cone/Cone-Rod Dystrophy Pathology by AAV-Mediated Overexpression of Mutant CRX Protein in the Mouse Retina.
Translational vision science & technology Jun, 2021 | Pubmed ID: 34144598
Geographic variations in idiopathic epiretinal membranes in China.
Annals of translational medicine Jun, 2021 | Pubmed ID: 34350253
Safety of Receiving Anti-Vascular Endothelial Growth Factor Intravitreal Injection in Office-Based vs Operating Room Settings: A Meta-analysis.
JAMA ophthalmology Oct, 2021 | Pubmed ID: 34410325
Improvement of human embryonic stem cell-derived retinal pigment epithelium cell adhesion, maturation, and function through coating with truncated recombinant human vitronectin.
International journal of ophthalmology , 2021 | Pubmed ID: 34414078
Retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGA1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2021 | Pubmed ID: 34418172
Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment.
Cell death & disease Oct, 2021 | Pubmed ID: 34628463
CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration.
National science review May, 2020 | Pubmed ID: 34692105
Identification of a novel RPGR mutation associated with X-linked cone-rod dystrophy in a Chinese family.
BMC ophthalmology Nov, 2021 | Pubmed ID: 34800980
Synthetic anti-angiogenic genomic therapeutics for treatment of neovascular age-related macular degeneration.
Asian journal of pharmaceutical sciences Sep, 2021 | Pubmed ID: 34849167
Choroidal Changes in Eyes With Polypoidal Choroidal Vasculopathy After Anti-VEGF Therapy Imaged With Swept-Source OCT Angiography.
Investigative ophthalmology & visual science Dec, 2021 | Pubmed ID: 34860239
DIA Comparative Proteomic Analysis of Retro-oil Fluid and Vitreous Fluid From Retinal Detachment Patients.
Frontiers in molecular biosciences , 2021 | Pubmed ID: 34926578
Associations of sensory impairment and cognitive function in middle-aged and older Chinese population: The China Health and Retirement Longitudinal Study.
Journal of global health , 2021 | Pubmed ID: 34956639
The Association of Sleep Duration With Vision Impairment in Middle-Aged and Elderly Adults: Evidence From the China Health and Retirement Longitudinal Study.
Frontiers in medicine , 2021 | Pubmed ID: 35004745
Malondialdehyde-Modified Photoreceptor Outer Segments Promote Choroidal Neovascularization in Mice.
Translational vision science & technology Jan, 2022 | Pubmed ID: 35015060
HMGB2 causes photoreceptor death via down-regulating Nrf2/HO-1 and up-regulating NF-κB/NLRP3 signaling pathways in light-induced retinal degeneration model.
Free radical biology & medicine Mar, 2022 | Pubmed ID: 35091064
Publication Trends of Research on Polypoidal Choroidal Vasculopathy During 2001-2020: A 20-Year Bibliometric Study.
Frontiers in medicine , 2021 | Pubmed ID: 35174182
A novel and efficient murine model of Bietti crystalline dystrophy.
Disease models & mechanisms Mar, 2022 | Pubmed ID: 35230417
Cysteine Substitution and Calcium-Binding Mutations in cbEGF-Like Domains Are Associated With Severe Ocular Involvement in Patients With Congenital Ectopia Lentis.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 35237611
Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure.
Nature communications 03, 2022 | Pubmed ID: 35351879
Glaucoma Characterization by Machine Learning of Tear Metabolic Fingerprinting.
Small methods May, 2022 | Pubmed ID: 35388987
Contribution of Interleukin-17A to Retinal Degenerative Diseases.
Frontiers in immunology , 2022 | Pubmed ID: 35392087
Visual impairment and depression in China: a 7-year follow-up study from national longitudinal surveys.
BMJ open Apr, 2022 | Pubmed ID: 35477885
Prediction of the short-term efficacy of anti-VEGF therapy for neovascular age-related macular degeneration using optical coherence tomography angiography.
Eye and vision (London, England) May, 2022 | Pubmed ID: 35505390
Development and Validation of a Novel Metabolic Signature-Based Prognostic Model for Uveal Melanoma.
Translational vision science & technology May, 2022 | Pubmed ID: 35536719
Targeting C3b/C4b and VEGF with a bispecific fusion protein optimized for neovascular age-related macular degeneration therapy.
Science translational medicine Jun, 2022 | Pubmed ID: 35648811
Biscuit consumption and diabetic retinopathy incidence in adults in the United States.
Diabetology & metabolic syndrome Jul, 2022 | Pubmed ID: 35794635
Application of an innovative grid-based surveillance strategy to ensure elimination and prevent reintroduction of malaria in high-risk border communities in China.
BMC public health Jul, 2022 | Pubmed ID: 35836156
High glucose promotes IL-17A-induced gene expression through histone acetylation in retinal pigment epithelium cells.
International immunopharmacology Sep, 2022 | Pubmed ID: 35978498
Prevalence and Risk Factors of Glaucoma Among Chinese People From the China Health and Retirement Longitudinal Study.
Journal of glaucoma Oct, 2022 | Pubmed ID: 35980856
Construction of a ferroptosis-associated circRNA-miRNA-mRNA network in age-related macular degeneration.
Experimental eye research Nov, 2022 | Pubmed ID: 36044964
A tunable genome editing system of the prime editor mediated by dihydrofolate reductase.
Journal of genetics and genomics = Yi chuan xue bao Mar, 2023 | Pubmed ID: 36055523
Progression of Polypoidal Lesions Associated with Exudative Recurrence in Polypoidal Choroidal Vasculopathy.
Ophthalmology Feb, 2023 | Pubmed ID: 36152843
Fat mass and obesity-associated protein alleviates Aβ induced retinal pigment epithelial cells degeneration via PKA/CREB signaling pathway.
Cell biology international Mar, 2023 | Pubmed ID: 36378581
Aquaporin 11 alleviates retinal Müller intracellular edema through water efflux in diabetic retinopathy.
Pharmacological research Jan, 2023 | Pubmed ID: 36403720
A Novel Bispecific Fusion Protein Targeting C3b/C4b and VEGF in Patients With nAMD: A Randomized, Open-Label, Phase 1b Study.
American journal of ophthalmology Apr, 2023 | Pubmed ID: 36410472
Growth of nonexudative macular neovascularization in age-related macular degeneration: an indicator of biological lesion activity.
Eye (London, England) Jul, 2023 | Pubmed ID: 36434285
Cognitive Impairment in Phenotypic Leber Hereditary Optic Neuropathy Caused by Mutation in Nuclear Gene NDUFAF5.
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society Dec, 2022 | Pubmed ID: 36580434
PFKFB3 knockdown attenuates Amyloid β-Induced microglial activation and retinal pigment epithelium disorders in mice.
International immunopharmacology Feb, 2023 | Pubmed ID: 36638665
Residential greenness exposure and decreased prevalence of diabetic retinopathy: A nationwide analysis in China.
Environmental research Mar, 2023 | Pubmed ID: 36642124
CircRNA Uxs1/miR-335-5p/PGF axis regulates choroidal neovascularization via the mTOR/p70 S6k pathway.
Translational research : the journal of laboratory and clinical medicine Jun, 2023 | Pubmed ID: 36690073
OUTER RETINAL TUBULATION IN BIETTI CRYSTALLINE DYSTROPHY ASSOCIATED WITH THE RETINAL PIGMENT EPITHELIUM ATROPHY.
Retina (Philadelphia, Pa.) Apr, 2023 | Pubmed ID: 36729610
The cause of redetachment after vitrectomy with air tamponade for a cohort of 1715 patients with retinal detachment: an analysis of retinal breaks reopening.
Eye and vision (London, England) Feb, 2023 | Pubmed ID: 36732872
Predictive value of pigment epithelial detachment markers for visual acuity outcomes in neovascular age-related macular degeneration.
BMC ophthalmology Mar, 2023 | Pubmed ID: 36869310
The association between obesity and glaucoma in older adults: evidence from the China Health and Retirement Longitudinal Study.
Epidemiology and health , 2023 | Pubmed ID: 36915268
Bifidobacterium promotes retinal ganglion cell survival by regulating the balance of retinal glial cells.
CNS neuroscience & therapeutics Jun, 2023 | Pubmed ID: 36924268
METTL3-mediated m6A modification of HMGA2 mRNA promotes subretinal fibrosis and epithelial-mesenchymal transition.
Journal of molecular cell biology Aug, 2023 | Pubmed ID: 36945110
Repurposing picropodophyllin as a potential thyroid eye disease treatment via delaying mitotic clonal expansion through a patient-derived preclinical platform.
Clinical and translational medicine Apr, 2023 | Pubmed ID: 37012693
Association between previous cataract surgery and cognition among middle-aged and older Chinese: the China health and retirement longitudinal study (CHARLS).
BMC ophthalmology May, 2023 | Pubmed ID: 37259095
Chinese Guideline on the Management of Polypoidal Choroidal Vasculopathy (2022).
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih Jun, 2023 | Pubmed ID: 37263796
Diabetic retinopathy in China: Epidemiology, screening and treatment trends-A review.
Clinical & experimental ophthalmology Aug, 2023 | Pubmed ID: 37381613
Associations between blood pressure levels and diabetic retinopathy in patients with diabetes mellitus: A population-based study.
Heliyon Jun, 2023 | Pubmed ID: 37484372
High Myopia Normative Database of Peripapillary Retinal Nerve Fiber Layer Thickness to Detect Myopic Glaucoma in a Chinese Population.
Ophthalmology Jul, 2023 | Pubmed ID: 37499953
Rapid and Sensitive Diagnosis of Leber Hereditary Optic Neuropathy Variants Using CRISPR/Cas12a Detection.
The Journal of molecular diagnostics : JMD Aug, 2023 | Pubmed ID: 37517824
The association between glaucoma and all-cause mortality in middle-aged and elderly Chinese people: results from the China Health and Retirement Longitudinal Study.
Epidemiology and health , 2023 | Pubmed ID: 37536720
Macrophage promotes pathological neovascularization in age-related macular degeneration.
Life science alliance Nov, 2023 | Pubmed ID: 37550000
Prevalence and optical coherence tomography analyses of outer retinal tubulations in Chinese population with inherited retinal diseases.
Eye (London, England) Aug, 2023 | Pubmed ID: 37553355
AAV-mediated base-editing therapy ameliorates the disease phenotypes in a mouse model of retinitis pigmentosa.
Nature communications Aug, 2023 | Pubmed ID: 37582961
Nomogram of uveal melanoma as prediction model of metastasis risk.
Heliyon Aug, 2023 | Pubmed ID: 37609406
Genetic Factors and Characteristics on Spectral-Domain Optical Coherence Tomography Are Associated to Choroidal Thickness in ABCA4-Related Retinopathy Factors of Choroidal Thickness in ABCA4 Retinopathy.
Retina (Philadelphia, Pa.) Sep, 2023 | Pubmed ID: 37695977
Dynamic changes in macrophage morphology during the progression of choroidal neovascularization in a laser-induced choroidal neovascularization mouse model.
BMC ophthalmology Oct, 2023 | Pubmed ID: 37803306
Conducting gene therapy clinical trials based on natural history studies for inherited retinal diseases in Chinese population.
Advances in ophthalmology practice and research , 2023 | Pubmed ID: 37846429
Visual impairment and blindness caused by retinal diseases: A nationwide register-based study.
Journal of global health Nov, 2023 | Pubmed ID: 37921040
Shanghai Jiao Tong University School of Medicine
National Clinical Research Center for Eye Diseases
Shanghai Clinical Research Center for Eye Diseases
Shanghai Key Clinical Specialty
Shanghai Key Laboratory of Ocular Fundus Diseases
Shanghai Engineering Center for Visual Science and Photomedicine
Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases
Xinyue Bai*,1,2,3,4,5,6,7,
Ting Zhang*,1,2,3,4,5,6,7,
Xinyue Zhu1,2,3,4,5,6,7,
Xianyu Huang1,2,3,4,5,6,7,
Haiyun Liu1,2,3,4,5,6,7,
Xiaoyan Ding8,
Mei Jiang1,2,3,4,5,6,7,
Xiaodong Sun1,2,3,4,5,6,7
1Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine,
2, National Clinical Research Center for Eye Diseases,
3, Shanghai Clinical Research Center for Eye Diseases,
4, Shanghai Key Clinical Specialty,
5, Shanghai Key Laboratory of Ocular Fundus Diseases,
6, Shanghai Engineering Center for Visual Science and Photomedicine,
7, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases,
8Stem Cell Core Facility, CAS Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved