cryopreservation-human-embryonic-stem-cell-derived-retinal-pigment

Cryopreservation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells at the Optimal Stage

Retinal pigment epithelial&#160;(RPE) cells derived from human embryonic stem cells (hESCs) are superior cell sources for cell replacement therapy in ...

Shanghai Jiao Tong University School of Medicine

National Clinical Research Center for Eye Diseases

Shanghai Clinical Research Center for Eye Diseases

Shanghai Key Clinical Specialty

Shanghai Key Laboratory of Ocular Fundus Diseases

Shanghai Engineering Center for Visual Science and Photomedicine

Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases

To explore an xeno-free and defined coating substrate suitable for the culture of H9 human embryonic stem cell-derived retinal pigment epithelial (hES-RPE) cells , and compare the behaviors and functions of hES-RPE cells on two culture substrates, laminin521 (LN-521) and truncated recombinant human vitronectin (VTN-N).

Improvement of human embryonic stem cell-derived retinal pigment epithelium cell adhesion, maturation, and function through coating with truncated recombinant human vitronectin.

This study aimed to establish a novel choroidal neovascularization (CNV) mouse model through subretinally injecting malondialdehyde (MDA)-modified photoreceptor outer segments (POS), which was more consistent with the pathogenesis of wet age-related macular degeneration (AMD).

Malondialdehyde-Modified Photoreceptor Outer Segments Promote Choroidal Neovascularization in Mice.

Polypoidal choroidal vasculopathy (PCV) is a special subtype of AMD, which is one of the leading threats to vision health worldwide. At this time, many aspects of PCV, from how it works to potential treatments, remain a mystery. In this study, we explored the frontier researches and revealed the study trends within the study of PCV.

Publication Trends of Research on Polypoidal Choroidal Vasculopathy During 2001-2020: A 20-Year Bibliometric Study.

To explore the longitudinal association between visual impairment (VI) and depression among adults 45 years and older in China based on a nationally representative follow-up dataset.

Visual impairment and depression in China: a 7-year follow-up study from national longitudinal surveys.

Foods have a considerable influence on human health and were directly related to glycemic control for diabetes patients. However, little is known about the effects of biscuits, a traditional food consumed in large amounts in several countries, on diabetic retinopathy. This study aimed to explore the association between biscuit consumption and diabetic retinopathy prevalence in adults of the United States population.

Biscuit consumption and diabetic retinopathy incidence in adults in the United States.

Cataract is the primary cause of blindness globally, and surgery offers the only method by which to remove cataracts. We aimed to examine whether previous cataract surgery is associated with cognitive function.

Association between previous cataract surgery and cognition among middle-aged and older Chinese: the China health and retirement longitudinal study (CHARLS).

Since the poor prognosis of uveal melanoma with distant metastasis, we intended to screen out possible biomarkers for uveal melanoma metastasis risk and establish a nomogram model for predicting the risk of uveal melanoma (UVM) metastasis.

Article	Year
Improvement of human embryonic stem cell-derived retinal pigment epithelium cell adhesion, maturation, and function through coating with truncated recombinant human vitronectin. International journal of ophthalmology\| PubMed ID: 34414078	2021
Malondialdehyde-Modified Photoreceptor Outer Segments Promote Choroidal Neovascularization in Mice. Translational vision science & technology\| PubMed ID: 35015060	2022
Publication Trends of Research on Polypoidal Choroidal Vasculopathy During 2001-2020: A 20-Year Bibliometric Study. Frontiers in medicine\| PubMed ID: 35174182	2021
Visual impairment and depression in China: a 7-year follow-up study from national longitudinal surveys. BMJ open\| PubMed ID: 35477885	2022
Biscuit consumption and diabetic retinopathy incidence in adults in the United States. Diabetology & metabolic syndrome\| PubMed ID: 35794635	2022
Association between previous cataract surgery and cognition among middle-aged and older Chinese: the China health and retirement longitudinal study (CHARLS). BMC ophthalmology\| PubMed ID: 37259095	2023
Nomogram of uveal melanoma as prediction model of metastasis risk. Heliyon\| PubMed ID: 37609406	2023

Xinyue Zhu

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