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Department of Chemistry
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Calcium binding rigidifies the C2 domain and the intradomain interaction of GIVA phospholipase A2 as revealed by hydrogen/deuterium exchange mass spectrometry.
The Journal of biological chemistry Apr, 2008 | Pubmed ID: 18211893
A phospholipid substrate molecule residing in the membrane surface mediates opening of the lid region in group IVA cytosolic phospholipase A2.
The Journal of biological chemistry Nov, 2008 | Pubmed ID: 18753135
Analysis of conformational changes during activation of protein kinase Pak2 by amide hydrogen/deuterium exchange.
The Journal of biological chemistry Dec, 2008 | Pubmed ID: 18984590
2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides.
Bioorganic & medicinal chemistry Jul, 2009 | Pubmed ID: 19443224
Localizing the membrane binding region of Group VIA Ca2+-independent phospholipase A2 using peptide amide hydrogen/deuterium exchange mass spectrometry.
The Journal of biological chemistry Aug, 2009 | Pubmed ID: 19556238
Reciprocally coupled residues crucial for protein kinase Pak2 activity calculated by statistical coupling analysis.
PloS one , 2010 | Pubmed ID: 20209159
Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.
Journal of medicinal chemistry May, 2010 | Pubmed ID: 20369880
Lipoprotein-associated phospholipase A(2) interacts with phospholipid vesicles via a surface-disposed hydrophobic α-helix.
Biochemistry Jun, 2011 | Pubmed ID: 21553808
Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention.
Chemical reviews Oct, 2011 | Pubmed ID: 21910409
Essential role of ELOVL4 in very long chain fatty acid synthesis and retinal function.
The Journal of biological chemistry Dec, 2011 | Pubmed ID: 22199362
Tunghai University
Yuan-Hao Hsu1,
Jolinda A. Traugh2
1Department of Chemistry, Tunghai University,
2Department of Biochemistry, University of California, Riverside
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