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Radboudumc, Amalia Children’s Hospital

1 ARTICLES PUBLISHED IN JoVE

Genetics

Exploring X Chromosomal Aberrations in Ovarian Cells by Using Fluorescence In Situ Hybridization

Sapthami Nadesapillai¹, Janielle van der Velden², Didi Braat¹, Kathrin Fleischer^1,3, Ronald Peek¹

¹Department of Obstetrics and Gynecology, Radboudumc, ²Department of Pediatrics, Radboudumc, Amalia Children’s Hospital, ³Department of Reproductive Medicine, Nij Geertgen Center for Fertility

This article presents two methods based on fluorescence in situ hybridization to determine the X chromosomal content of ovarian cells in non-grafted and grafted ovarian cortex tissue from females with X chromosomal aberrations.