Synthesis of Esters Via a Greener Steglich Esterification in AcetonitrileAndrew B. Lutjen 1, Mackenzie A. Quirk 1, Erin M. Kolonko 1
1Department of Chemistry and Biochemistry, Siena College
A modified Steglich esterification reaction was used to synthesize a small library of ester derivatives with primary and secondary alcohols. The methodology uses a non-halogenated and greener solvent, acetonitrile, and enables product isolation in high yields without the need for chromatographic purification.
