A Simple Method for High Throughput Chemical Screening in Caenorhabditis ElegansMark Lucanic 1, Theo Garrett 1, Matthew S. Gill 2, Gordon J. Lithgow 1
1The Buck Institute for Research on Aging, 2The Scripps Research Institute Center on Aging
Here we describe a simple protocol for rapidly producing hundreds of nematode growth media agar, 96-well culture plates with consistent numbers of Caenorhhabditis elegans per well. These cultures are useful for the phenotypic screening of whole organisms. We focus here on using these cultures to screen chemicals for pro-longevity effects.
