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Helmholtz-Institute of RWTH Aachen University

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Medicine

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Sakine Simsekyilmaz 1, Fabian Schreiber 2, Stefan Weinandy 3, Felix Gremse 4, Tolga Taha Sönmez 5, Elisa A. Liehn 1
1Institute for Molecular Cardiovascular Research, RWTH Aachen University, 2Institute for Textile Technology and Mechanical Engineering, RWTH Aachen University, 3Institute for Applied Medical Engineering, Helmholtz-Institute of RWTH Aachen University, 4Department of Experimental Molecular Imaging, RWTH Aachen University, 5Department of Oral and Maxillofacila Surgery, RWTH Aachen University

A model of stent implantation in mouse carotid artery is described. Compared to other similar methods, this procedure is very rapid, simple and accessible, offering the possibility to study in a convenient way the vascular wall reaction to different drug-eluting stents and the molecular mechanisms of restenosis.

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