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Georgia Institute of Technology & Emory University School of Medicine

1 ARTICLES PUBLISHED IN JoVE

JoVE Core

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States

Natalie K. Fan¹, Philip M. Keegan¹, Manu O. Platt^1,2, Rodney D. Averett^2,3

¹Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, ²Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, ³George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology

In this manuscript, experimental techniques, including blood preparation, confocal microscopy, and lysis rate analysis, to examine the morphological differences between normal and abnormal clot structures due to diseased states are presented.