Implantation of Miniosmotic Pumps and Delivery of Tract Tracers to Study Brain Reorganization in Pathophysiological ConditionsEduardo H. Sanchez-Mendoza 1, Jeismar Carballo 1,2,3, Marines Longart 2, Dirk M. Hermann 1, Thorsten R. Doeppner 1
1Department of Neurology, University of Duisburg-Essen, 2Neuroscience Unit, Institute for Advanced Studies (IDEA), 3Department of Cell Biology, Simon Bolivar University
In order to study brain reorganization under pathological conditions we used miniosmotic pumps for direct protein delivery into the brain circumventing the blood brain barrier. Tract tracers are then injected to study alterations in brain connectivity under the influence of the protein.
