DNAzyme 10-23 - Based Nanomachines for Nucleic Acid RecognitionPavel V. Filatov 1, Muhannad Ateiah 1, Maria Y. Berezovskaya 1, Maria S. Rubel 1, Dmitry M. Kolpashchikov 2
1ITMO University, 2University of Central Florida
The DNAzyme-based nanomachines can be used for highly selective and sensitive detection of nucleic acids. This article describes a detailed protocol for the design of DNAzyme-based nanomachines with a 10-23 core using free software and their application in the detection of an Epstein-Barr virus fragment as an example.
