Investigating Protein-protein Interactions in Live Cells Using Bioluminescence Resonance Energy TransferPelagia Deriziotis *1, Sarah A. Graham *1, Sara B. Estruch 1, Simon E. Fisher 1,2
1Language and Genetics Department, Max Planck Institute for Psycholinguistics, 2Donders Institute for Brain, Cognition and Behaviour
Interactions between proteins are fundamental to all cellular processes. Using Bioluminescence Resonance Energy Transfer, the interaction between a pair of proteins can be monitored in live cells and in real time. Furthermore, the effects of potentially pathogenic mutations can be assessed.
