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Zhejiang Provincial People's Hospital

2 ARTICLES PUBLISHED IN JoVE

Medicine

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment

Mei Wang¹, Zhengluan Liao², Dewang Mao³, Qi Zhang¹, Yumei Li³, Enyan Yu², Zhongxiang Ding³

¹Zhejiang Chinese Medical University, ²Department of Psychiatry, Zhejiang Provincial People's Hospital, ³Department of Radiology, Zhejiang Provincial People's Hospital

Based on resting-state functional magnetic resonance imaging with Granger causality analysis, we investigated the alterations in the directed functional connectivity between the posterior cingulate cortex and whole brain in patients with Alzheimer's Disease (AD), patients with Mild Cognitive Impairment (MCI), and healthy controls.

Developmental Biology

Preparing Activated Platelet-Rich Plasma for Culturing Human Adipose-Derived Stem Cells

Fangyuan Lai^1,2, Natsuko Kakudo¹, Naoki Morimoto¹, Yuanyuan Ma¹, Kenji Kusumoto¹

¹Department of Plastic and Reconstructive Surgery, Kansai Medical University, ²Department of Plastic Surgery, Zhejiang Provincial People's Hospital

In this report, we describe a double-spin method for preparing activated platelet-rich plasma (PRP). Using autologous thrombin, human adipose-derived stem cells (hASCs) were cultured. Activated PRP was shown to promote proliferation of hASCs.