High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass SpectrometryMeera Shanmuganathan 1, Sabrina Macklai 1, Clara Barrenas Cárdenas 1, Zachary Kroezen 1, Marcus Kim 2, William Zizek 3, Howard Lee 3, Philip Britz-McKibbin 1
1Department of Chemistry and Chemical Biology, McMaster University, 2Agilent Technologies Inc., 3Seroclinix Corporation
Here we describe a high-throughput method for comprehensive drug surveillance that allows for the improved resolution and detection of large panels of drugs of abuse and their metabolites, with quality control based on multisegment injection-capillary electrophoresis-mass spectrometry.
