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Manchester Metropolitan University

3 ARTICLES PUBLISHED IN JoVE

Behavior

Using Chronic Social Stress to Model Postpartum Depression in Lactating Rodents

Lindsay M. Carini¹, Christopher A. Murgatroyd², Benjamin C. Nephew¹

¹Biomedical Sciences, Tufts University Cummings School of Veterinary Medicine, ²School of Healthcare Sciences, Manchester Metropolitan University

This article describes the use of chronic resident intruder social stress as an ethologically relevant paradigm to model postpartum depression and anxiety in lactating rodents.

Chemistry

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Michael G. Apps¹, Ben W. Johnson², Oliver B. Sutcliffe³, Sarah D. Brown⁴, Nial J. Wheate¹

¹Faculty of Pharmacy, The University of Sydney, ²School of Science and Health, University of Western Sydney, ³Division of Chemistry and Environmental Science, School of Science and the Environment, Manchester Metropolitan University, ⁴Nature Publishing Group

This protocol describes the use of amide coupling reactions of isonicotinic acid and diaminoalkanes to form bridging ligands suitable for use in the synthesis of multinuclear platinum complexes, which combine aspects of the anticancer drugs BBR3464 and picoplatin.

Environment

Spotting Cheetahs: Identifying Individuals by Their Footprints

Zoe C. Jewell¹, Sky K. Alibhai¹, Florian Weise^2,3, Stuart Munro², Marlice Van Vuuren⁴, Rudie Van Vuuren⁴

¹WildTrack and Nicholas School of the Environment, Duke University, ²N∕a′an ku sê Research Programme, ³Division of Biology and Conservation Ecology, School of Science and the Environment, Manchester Metropolitan University, ⁴N∕a′an ku sê Foundation

The cheetah (Acinonyx jubatus) is an iconic, endangered species, but conservation efforts are challenged by habitat shrinkage and conflict with commercial farmers. The footprint identification technique, a robust, accurate and cost-effective image classification system, is a new approach to monitoring cheetahs.