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Göttingen, Germany

2 ARTICLES PUBLISHED IN JoVE

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Medicine

Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)
René Günther 1, Martin Suhr 1, Jan C. Koch 1, Mathias Bähr 1,2, Paul Lingor 1,2, Lars Tönges 1
1Dept. of Neurology, University Medicine Göttingen, 2DFG Research Center for the Molecular Physiology of the Brain (CMPB), Göttingen, Germany

A mouse model for amyotrophic lateral sclerosis (ALS) is examined clinically and behaviorally. As a prerequisite for an accompanying immunohistological analysis the preparation of the spinal cord is depicted in detail.

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Neuroscience

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Katharina Schregel 1,2, Daniel Behme 1, Ioannis Tsogkas 1, Michael Knauth 1, Ilko Maier 3, André Karch 4, Rafael Mikolajczyk 4,5, Mathias Bähr 3, Jörn Schäper 6, José Hinz 6, Jan Liman 3, Marios-Nikos Psychogios 1
1Institute of Neuroradiology, University Medical Center Goettingen, 2Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, 3Department of Neurology, University Medical Center Goettingen, 4Department of Epidemiology, Helmholtz Center for Infection Research, 5Institute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg, 6Department of Anesthesiology, University Medical Center Goettingen

The outcome of patients with acute ischemic stroke depends on swift restoration of cerebral blood flow. This protocol aims at optimizing the management of such patients by minimizing peri-procedural timings and rendering the time from hospital admission to reperfusion as short as possible.

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