Whole Mount Immunofluorescent Staining of the Neonatal Mouse Retina to Investigate Angiogenesis In vivoSimon Tual-Chalot 1, Kathleen R. Allinson 1, Marcus Fruttiger 2, Helen M. Arthur 1
1Institute of Genetic Medicine, Newcastle University , 2UCL Institute of Ophthalmology, University College, London
The neonatal murine retina provides a well characterized physiological model of angiogenesis, which permits investigations of the roles of different genes or drugs that modulate angiogenesis in an in vivo context. Immunofluorescent staining to accurately visualize the vascular plexus is pivotal to the success of these types of studies.
