A New Murine Model of Endovascular Aortic Aneurysm RepairMartin Rouer 1, Olivier Meilhac 1, Sandrine Delbosc 1, Liliane Louedec 1, Graciela Pavon-Djavid 1,2, Jane Cross 3, Josette Legagneux 4, Maxime Bouilliant-Linet 4, Jean-Baptiste Michel 1, Jean-Marc Alsac 1,5
1INSERM U698 Cardiovascular Remodelling, Hôpital X. Bichat, AP-HP, Paris, 2Bio-Ingénierie des Polymères Cardiovasculaires (BPC), Institut Galilée - Université Paris 13, Paris, France, 3Service de Chirurgie Vasculaire, Hôpital Henri Mondor, AP-HP, Université Paris-Est Creteil, 4Ecole de chirurgie de l'assistance publique des hôpitaux de Paris, 5Service de Chirurgie Cardiaque et Vasculaire, Hôpital Européen Georges Pompidou, AP-HP, Université René Descartes
Histological and biochemical modifications after aneurysm endograft exclusion are still unclear. We describe a new model of endograft implantation on a murine aneurysm. Through thrombus analysis with and without persistant circulating blood stream interface, and new endovascular biomaterials evaluation, this model will help to better understand endovascular aneurysm exclusion pathobiology.
