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North Carolina State University and University of North Carolina at Chapel Hill

1 ARTICLES PUBLISHED IN JoVE

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Bioengineering

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
Darryl A. Boyd 1, Andre A. Adams 1, Michael A. Daniele 1, Frances S. Ligler 1,2
1Center for Bio/Molecular Science & Engineering, US Naval Research Laboratory, 2Joint Department of Biomedical Engineering, North Carolina State University and University of North Carolina at Chapel Hill

Two adjacent fluids passing through a grooved microfluidic channel can be directed to form a sheath around a prepolymer core; thereby determining both shape and cross-section. Photoinitiated polymerization, such as thiol click chemistry, is well suited for rapidly solidifying the core fluid into a microfiber with predetermined size and shape.

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