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La Pitié-Salpêtrière Hospital, AP-HP, Sorbonne and Pierre and Marie Curie University

1 ARTICLES PUBLISHED IN JoVE

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Medicine

Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue
Elena Dossi 1, Thomas Blauwblomme 2,3, Rima Nabbout 2,4, Gilles Huberfeld 2,5, Nathalie Rouach 1
1Neuroglial Interactions in Cerebral Physiopathology, Center for Interdisciplinary Research in Biology, CNRS UMR 7241, INSERM U1050, Collège de France, 2Infantile Epilepsies & Brain Plasticity, INSERM U1129, PRES, Paris Descartes University, Sorbonne Paris Cité, CEA, 3Neurosurgery Department, Necker Hospital, AP-HP, Paris Descartes University, 4Rare Epilepsies Reference Center, Necker Hospital, AP-HP, Paris Descartes University, 5Neurophysiology Department, La Pitié-Salpêtrière Hospital, AP-HP, Sorbonne and Pierre and Marie Curie University

We here describe how to perform multi-electrode array recordings of human epileptic cortical tissue. Epileptic tissue resection, slice preparation and multi-electrode array recordings of interictal and ictal events are demonstrated in detail.

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