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Robert-Bosch-Krankenhaus

3 ARTICLES PUBLISHED IN JoVE

Medicine

Intracoronary Acetylcholine Provocation Testing for Assessment of Coronary Vasomotor Disorders

Peter Ong¹, Anastasios Athanasiadis¹, Udo Sechtem¹

¹Department of Cardiology, Robert-Bosch-Krankenhaus

Intracoronary acetylcholine testing has been established for the assessment of epicardial coronary spasm more than 30 years ago. Recently, the focus has shifted towards the microcirculation and it has been shown that microvascular spasm can be detected using ACH-testing. This article describes the ACH-test and its implementation in daily routine.

Immunology and Infection

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury

Natalie Burkard¹, Wolfgang Baar^2,3, Sven Flemming¹, Nicolas Schlegel¹, Jakob Wollborn^2,3, Reinhard Schneider⁴, Robert W Brock⁵, Christian Wunder⁶, Martin Alexander Schick^2,3

¹Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, Department of Surgery I, University of Würzburg, ²Department of Anesthesiology and Critical Care, Medical Center-University of Freiburg, ³Faculty of Medicine, University of Freiburg, ⁴Department of Internal Medicine I, Division of Nephrology, University of Würzburg, ⁵Department of Physiology and Pharmacology, West Virginia University School of Medicine, Robert C. Byrd Health Science Center, ⁶Department of Anesthesiology and Intensive Care Medicine, Robert-Bosch-Krankenhaus

Acute kidney injury (AKI) is a severe complication in critically ill patients and is related with an increased mortality. Here, we present a reliable and reproducible in vivo model to mimic AKI under inflammatory conditions that might contribute towards understanding the pathogenesis of septic AKI.

Invasive Assessments For Coronary Vasomotor Disorders: Current State of the Art Methods Collection

Peter Ong¹, Colin Berry², Andreas Seitz¹

¹Department of Cardiology and Angiology, Robert-Bosch-Krankenhaus, ²Department of Cardiology, Golden Jubilee National Hospital, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow

Invasive Assessments For Coronary Vasomotor Disorders: Current State of the Art Methods Collection