Comprehensive DNA Methylation Analysis Using a Methyl-CpG-binding Domain Capture-based Method in Chronic Lymphocytic Leukemia PatientsSanthilal Subhash 1, Meena Kanduri 2
1Department of Medical Genetics, Institute of Biomedicine, Gothenburg University, 2Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, Gothenburg University
This work describes an optimized methyl-CpG-binding domain (MBD) sequencing protocol and a computational pipeline to identify differentially methylated CpG-rich regions in chronic lymphocytic leukemia (CLL) patients.
