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University Duisburg-Essen

3 ARTICLES PUBLISHED IN JoVE

Medicine

Application of an Amplitude-integrated EEG Monitor (Cerebral Function Monitor) to Neonates

Nora Bruns¹, Susanne Blumenthal¹, Irmgard Meyer¹, Susanne Klose-Verschuur¹, Ursula Felderhoff-Müser¹, Hanna Müller^1,2

¹Department of Pediatrics I, Neonatology, Pediatric Intensive Care, Pediatric Neurology, University Hospital Essen, University Duisburg-Essen, ²Division of Neonatology, Department of Pediatrics, University of Heidelberg

Here, we show how to apply amplitude-integrated electroencephalography to monitor cerebral function in neonates.

Environment

Identification of Pharmaceuticals in The Aquatic Environment Using HPLC-ESI-Q-TOF-MS and Elimination of Erythromycin Through Photo-Induced Degradation

Melanie Voigt^1,2, Christina Savelsberg¹, Martin Jaeger¹

¹Niederrhein University of Applied Sciences, ²University Duisburg-Essen

We present a protocol for non-targeted analysis using time of flight mass spectrometry as a perfect tool to identify pharmaceuticals in waters. We demonstrate the application of UV irradiation for their elimination. Analysis involving irradiation, compound isolation, identification and kinetic modelling of the degradation profiles is illustrated.

Medicine

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children

Nora Bruns¹, Julia Moosmann², Frank Münch³, Christian Dohna-Schwake¹, Joachim Woelfle⁴, Robert Cesnjevar³, Sven Dittrich², Ursula Felderhoff-Müser¹, Hanna Müller⁴

¹Department of Pediatrics I - Neonatology, Pediatric Intensive Care, Pediatric Neurology, University Hospital Essen, University of Duisburg-Essen, ²Department of Pediatric Cardiology, University Hospital Erlangen, University of Erlangen-Nürnberg, ³Department of Pediatric Cardiac Surgery, University Hospital Erlangen, University of Erlangen-Nürnberg, ⁴Division of Neonatology and Pediatric Intensive Care, Department of Pediatrics, University Hospital Erlangen, University of Erlangen-Nürnberg

This protocol is designed to assist clinicians to measure regional tissue oxygenation at different body sites in infants and children. It can be used in situations where tissue oxygenation is potentially compromised, particularly during cardiopulmonary bypass, when using non-pulsatile cardiac-assist devices, and in critically ill neonates, infants and children.