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Czech Technical University in Prague, Czech Republic

3 ARTICLES PUBLISHED IN JoVE

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Neuroscience

Autonomous and Rechargeable Microneurostimulator Endoscopically Implantable into the Submucosa
Jan Hajer *1,2, Marek Novák *3
12nd Department of Internal Medicine, Third Faculty of Medicine, Charles University, Prague, Czech Republic, 22nd Department of Internal Medicine, University Hospital Královské Vinohrady, Prague, Czech Republic, 3Czech Technical University in Prague, Czech Republic

The application of high-frequency low-energetic stimulation can alleviate the symptoms of gastric dysmotility. In this research, a miniature, endoscopically implantable and wirelessly rechargeable device which is implanted into a submucosal pocket is presented. Successful both-way communication and stimulation control were achieved during an experiment on live pig.

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Engineering

Methods of Ex Situ and In Situ Investigations of Structural Transformations: The Case of Crystallization of Metallic Glasses
Marcel B. Miglierini 1,2, Vít Procházka 3, Vlastimil Vrba 3, Peter Švec 4, Dušan Janičkovič 4, Peter Matúš 5
1Institute of Nuclear and Physical Engineering, Slovak University of Technology in Bratislava, Slovakia, 2Department of Nuclear Reactors, Czech Technical University in Prague, Czech Republic, 3Department of Experimental Physics, Palacky University Olomouc, Czech Republic, 4Institute of Physics, Slovak Academy of Sciences, Bratislava, Slovakia, 5Institute of Laboratory Research on Geomaterials, Faculty of Natural Sciences, Comenius University in Bratislava, Slovakia

Here, we present a protocol to describe ex situ and in situ investigations of structural transformations in metallic glasses. We employed nuclear-based analytical methods which inspect hyperfine interactions. We demonstrate the applicability of Mössbauer spectrometry and nuclear forward scattering of synchrotron radiation during temperature-driven experiments.

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Bioengineering

Construction of a Wireless-Enabled Endoscopically Implantable Sensor for pH Monitoring with Zero-Bias Schottky Diode-based Receiver
Marek Novák 1, Jozef Rosina 1, Robert Gürlich 2, Ivana Cibulková 3, Jan Hajer 3
1Department of Medical Biophysics and Medical Informatics, Third Faculty of Medicine, Charles University, 2Department of General Surgery, Third Faculty of Medicine, Charles University, University Hospital Královské Vinohrady, 3Department of Internal Medicine, Third Faculty of Medicine, Charles University, University Hospital Královské Vinohrady

The manuscript presents a miniature implantable pH sensor with ASK modulated wireless output together with a fully passive receiver circuit based on zero-bias Schottky diodes. This solution can be used as a basis in the development of in vivo calibrated electrostimulation therapy devices and for ambulatory pH monitoring.

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