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Tamkang University

2 ARTICLES PUBLISHED IN JoVE

Immunology and Infection

Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds

Chen-Jei Tai^1,2, Chia-Lin Li³, Cheng-Jeng Tai^4,5, Chien-Kai Wang^2,4, Liang-Tzung Lin^3,6

¹Department of Chinese Medicine, Taipei Medical University Hospital, ²Department of Obstetrics and Gynecology, School of Medicine, College of Medicine, Taipei Medical University, ³Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, ⁴Division of Hematology and Oncology, Department of Internal Medicine, Taipei Medical University Hospital, ⁵Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, ⁶Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University

Here, we present a protocol that examines specific steps of the viral entry to identify and evaluate novel antiviral agents.

Engineering

One-Step Approach to Fabricating Polydimethylsiloxane Microfluidic Channels of Different Geometric Sections by Sequential Wet Etching Processes

Chien-Kai Wang^1,2, Wei-Hao Liao¹, Hsiao-Mei Wu¹, Yi-Chung Tung^1,3

¹Research Center for Applied Sciences, Academia Sinica, ²Department of Civil Engineering, Tamkang University, ³College of Engineering, Chang Gung University

Several methods are available for the fabrication of channels of non-rectangular sections embedded in polydimethylsiloxane microfluidic devices. Most of them involve multistep manufacturing and extensive alignment. In this paper, a one-step approach is reported for fabricating microfluidic channels of different geometric cross sections by polydimethylsiloxane sequential wet etching.