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1 ARTICLES PUBLISHED IN JoVE

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Engineering

Development of a Nose-only Inhalation Toxicity Test Chamber That Provides Four Exposure Concentrations of Nano-sized Particles
Jae-Seong Yi 1,2, Ki-Soo Jeon 2, Hee-Jung Kim 2, Ki-Joon Jeon 1, Il-Je Yu 2
1Department of Environmental Engineering, Inha University, 2HCTM Co. Ltd

A nose-only inhalation toxicity chamber capable of testing inhalation toxicity at four different exposure concentrations was designed and validated for flow field uniformity and cross-contamination between the exposure ports for each concentration. Here, we present a protocol to confirm that the designed chamber is effective for inhalation toxicity testing.

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