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Institut Paoli-Calmettes, CRCM

1 ARTICLES PUBLISHED IN JoVE

Biochemistry

Profiling Ubiquitin and Ubiquitin-like Dependent Post-translational Modifications and Identification of Significant Alterations

Mirna Swayden¹, Aurélie Dobric¹, Yolande Berthois¹, Hugo Villalba¹, Stéphane Audebert¹, Luc Camoin¹, Juan Iovanna¹, Philippe Soubeyran¹

¹Aix-Marseille Univ, INSERM, CNRS, Institut Paoli-Calmettes, CRCM

This protocol aims at establishing ubiquitin (Ub) and ubiquitin-likes (Ubls) specific proteomes in order to identify alterations of these kind of post-translational modifications (PTMs), associated with a specific condition such as a treatment or a phenotype.