Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to DegenerationFlorian Christof Bonnaire 1,2, Martina Feierabend 3, Julius Michael Wolfgart 1,4, Wolfram Breuer 5, Christian Walter 2, Ulf Krister Hofmann 1,2, Marina Danalache 1
1Laboratory of Cell Biology, Department of Orthopedic Surgery, University Hospital of Tübingen, 2Department of Orthopedic Surgery, University Hospital of Tübingen, 3Institute for Bioinformatics and Medical Informatics, Faculty of science of the University of Tübingen, 4Medical faculty of the University of Tübingen, 5Bavarian Health and Food Safety Authority
We present a method to investigate spatial chondrocyte organization in the anulus fibrosus of the intervertebral disc using an optical sectioning method.