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College of St. Benedict/St. John’s University

1 ARTICLES PUBLISHED IN JoVE

Biochemistry

Modeling an Enzyme Active Site using Molecular Visualization Freeware

Kristen Procko¹, Sandy Bakheet¹, Josh T. Beckham¹, Margaret A. Franzen², Henry Jakubowski³, Walter R. P. Novak⁴

¹The University of Texas at Austin, ²Mount Mary University, ³College of St. Benedict/St. John’s University, ⁴Wabash College

A key skill in biomolecular modeling is displaying and annotating active sites in proteins. This technique is demonstrated using four popular free programs for macromolecular visualization: iCn3D, Jmol, PyMOL, and UCSF ChimeraX.