Traumatic Peripheral Nerve Injury in MiceJung Il Lee *1, Prem Kumar Govindappa *2, Grant D. Wandling 2, John C. Elfar 2
1Department of Orthopaedic Surgery, Korea University Guro Hospital, 2Department of Orthopaedics and Rehabilitation, Center for Orthopaedics and Translational Science, The Pennsylvania State University College of Medicine
The present protocol describes traumatic peripheral nerve injuries (TPNIs), including precisely calibrated crush, strictly aligned and misaligned laceration, as well as grafted and non-grafted gaps of the sciatic nerve in mice. Custom-designed sensors are developed to gauge nerve trauma, induced with commonly available tools to ensure reproducible post-TPNI outcomes.
