Antibodies, also known as immunoglobulins, are produced by B cells in response to foreign substances, such as bacteria and viruses. These proteins are critical for recognizing and neutralizing these substances, protecting the body from potential harm.

The basic structure of an antibody consists of four protein chains: two identical heavy chains and two identical light chains. These chains are held together by disulfide bonds and other non-covalent interactions, forming a Y-shaped structure. Each chain features distinct regions that contribute to the overall function of the antibody.

The variable region, found at the tips of the heavy and light chains, is responsible for antigen recognition. Conversely, the constant region, located at the base of the heavy and light chains, determines the effector functions of the antibody, eliciting appropriate immune responses.

There are several classes of antibodies, including IgG, IgM, IgA, IgD, and IgE, each distinguished by a unique constant region. These classes have different roles in the immune response. For instance, IgG antibodies neutralize pathogens and activate complement, IgA antibodies protect mucosal surfaces, and IgE antibodies play a role in allergic reactions.

Tags
AntibodiesImmunoglobulinsB CellsAntigen RecognitionVariable RegionConstant RegionImmune ResponseAntibody ClassesIgGIgMIgAIgDIgEDisulfide BondsY shaped Structure

Del capítulo 25:

article

Now Playing

25.26 : Antibody Structure and Classes

The Lymphatic and Immune System

528 Vistas

article

25.1 : Introducción al sistema linfático e inmunológico

The Lymphatic and Immune System

1.3K Vistas

article

25.2 : Funciones del sistema linfático e inmunológico

The Lymphatic and Immune System

616 Vistas

article

25.3 : Vasos linfáticos y transporte linfático

The Lymphatic and Immune System

643 Vistas

article

25.4 : Células y tejidos linfoides

The Lymphatic and Immune System

424 Vistas

article

25.5 : Órganos linfoides primarios

The Lymphatic and Immune System

592 Vistas

article

25.6 : Órganos linfoides secundarios

The Lymphatic and Immune System

472 Vistas

article

25.7 : Estructura y función detalladas de los ganglios linfáticos

The Lymphatic and Immune System

492 Vistas

article

25.8 : Desarrollo del sistema linfático

The Lymphatic and Immune System

194 Vistas

article

25.9 : Introducción a la inmunidad innata y adaptativa

The Lymphatic and Immune System

2.7K Vistas

article

25.10 : Barreras de membrana superficial

The Lymphatic and Immune System

503 Vistas

article

25.11 : Células de la respuesta inmunitaria innata

The Lymphatic and Immune System

871 Vistas

article

25.12 : Proteínas antimicrobianas

The Lymphatic and Immune System

550 Vistas

article

25.13 : Sistema de complemento

The Lymphatic and Immune System

1.5K Vistas

article

25.14 : Vigilancia inmunitaria por células NK y fagocitos

The Lymphatic and Immune System

695 Vistas

See More

JoVE Logo

Privacidad

Condiciones de uso

Políticas

Investigación

Educación

ACERCA DE JoVE

Copyright © 2025 MyJoVE Corporation. Todos los derechos reservados