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Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

DOI :

10.3791/59635-v

August 9th, 2019

August 9th, 2019

6,485 Views

1Department of Molecular, Cellular and Developmental Biology, University of Colorado at Boulder

Sequence specificity is critical for gene regulation. Regulatory proteins that recognize specific sequences are important for gene regulation. Defining functional binding sites for such proteins is a challenging biological problem. An iterative approach for identification of a binding site for an RNA-binding protein is described here and is applicable to all RNA-binding proteins.

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Sequence Space

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