CT-FIRE Fiber Extraction and Region of Interest (ROI) Analysis
2:34
Advanced CT-FIRE Post-Processing
4:09
CurveAlign Fiber Analysis: CT Mode Without Boundary
5:03
CurveAlign Fiber Analysis: CT-FIRE Mode with Boundary
6:14
CurveAlign Region of Interest (ROI) Analysis
6:56
Results: Representative Tumor-Associated Human Breast Cancer Tissue Microarray (TMA) Collagen Signatures
7:26
Conclusion
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This tool helps to quantify changes in fibrillar collagen organization in the extracellular matrix related to many diseases on a global region of interest and individual fiber basis. This tool uses the curvelet transform, an optimal multi-scale di
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Here, we present a protocol to use a curvelet transform-based, open-source MATLAB software tool for quantifying fibrillar collagen organization in the extracellular matrix of both normal and diseased tissues. This tool can be applied to images with collagen fibers or other types of line-like structures.