Results: Characterization of Endoderm and 3D Whole Lung Organoids
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Conclusion
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This protocol uses induced pluripotent stem cells to differentiate them into lung cells in order to model human lung disease and development in a dish. This protocol is significant because it's difficult to obtain and culture primary human lung ti
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The article describes step wise directed differentiation of induced pluripotent stem cells to three-dimensional whole lung organoids containing both proximal and distal epithelial lung cells along with mesenchyme.